MODERN APPROACHES TO LABORATORY DIAGNOSIS OF RICKETTSIAL DISEASES

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Abstract

Abstract. We present a concise review of contemporary laboratory methods for diagnosis of rickettsioses with special emphasis on diseases known in Russian Federation. Classic and emerging rickettsioses are transmitted by a diverse and expanding group of arthropod vectors including ticks, fleas, lice and mites. While epidemiological and clinical clues can provide information important for initial suspicion of rickettsial infection, sensitive and specific laboratory methods are necessary for providing probable or confirmed diagnosis of the rickettsial infection. Accurate and rapid confirmation of rickettsial infection is important for ensuring proper clinical care and prompt initiation of antibiotic therapy. Correct identification of the etiology of rickettsial diseases is also important for early identification of clustered cases, novel foci of infections, and for timely initiation of public health responses to these potentially fatal infections.

About the authors

M. E. Eremeeva

Georgia Southern University, Statesboro, GA

Author for correspondence.
Email: meremeeva@georgiasouthern.edu

PhD, MD (Biology), Associate Professor, Director of the Public Health Core Laboratory

JPH COPH, Georgia Southern University, Statesboro, GA 30458, USA

 

United States

S. N. Shpynov

N.F. Gamaleya Institute of Epidemiology and Microbiology, Moscow

Email: meremeeva@georgiasouthern.edu
PhD, MD (Medicine), Head of Laboratory of Ecology of Rickettsiae Russian Federation

N. K. Tokarevich

St. Petersburg Pasteur Institute, St. Petersburg; North-Western State Medical University named after I.I. Mechnikov, St. Petersburg

Email: meremeeva@georgiasouthern.edu
PhD, MD (Medicine), Head of Laboratory of Zoonoses, St. Petersburg Pasteur Institute; Professor, Department of Epidemiology, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation Russian Federation

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