OPPORTUNITIES OF THE FLOW CYTOMETRY IN DIAGNOSTICS OF INFECTIOUS DISEASES. Part 3

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  • Authors: Khaidukov S.V.1, Zurochka A.V.2
  • Affiliations:
    1. Институт биоорганической химии им. акад. М.М. Шемякина и Ю.А. Овчинникова РАН, Москва ФГУ Федеральный Научно-Клинический Центр детской гематологии, онкологии и иммунологии РОСЗДРАВА, Москва
    2. Институт иммунологии и физиологии УрО РАН, г. Екатеринбург
  • Issue: Vol 1, No 3 (2011)
  • Pages: 221-230
  • Section: REVIEWS
  • Submitted: 30.06.2014
  • Accepted: 30.06.2014
  • Published: 30.06.2014
  • URL: https://iimmun.ru/iimm/article/view/50
  • DOI: https://doi.org/10.15789/2220-7619-2011-3-221-230
  • ID: 50


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Abstract

Abstract. Development of modern clinical and infectious immunology, demands maximum objective tests for estimation of functional condition of various types phagocytic cells, such as neutrophils, monocytes, macrophages and dendritic cells. Wide potential opportunities of flow cytometry have led to development of ways of registration of a functional condition of these cells, an estimation of processes of their activation and study of mechanisms formation of defects of their functions. For example: analysis of phagocytic and bactericidal activity of neutrophils and measurement number of the cells, which are taking place at various stages of programmed cellular death (apoptosis). Flow cytometry methods described in this review represent a new hi-tech direction for scientific and clinical researches.

About the authors

S. V. Khaidukov

Институт биоорганической химии им. акад. М.М. Шемякина и Ю.А. Овчинникова РАН, Москва

ФГУ Федеральный Научно-Клинический Центр детской гематологии, онкологии и иммунологии РОСЗДРАВА, Москва

Author for correspondence.
Email: khsv@mail.ibch.ru

д.б.н., зав. лабораторией физиологии и патологии иммунной системы

117997, Москва, ул. Миклухо-Маклая, 16/10

Россия

A. V. Zurochka

Институт иммунологии и физиологии УрО РАН, г. Екатеринбург

Email: khsv@mail.ibch.ru
Россия

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