ARGUMENTATION OF ACUTE RESPIRATORY VIRAL INFECTIONS NONSPECIFIC PREVENTION IN GROUPS OF CHILDREN

Cover Page


Cite item

Full Text

Abstract

Acute respiratory viral infections (ARVI) and influenza are among the topical problems of healthcare. The children’s morbidity index in preschool educational institutions in Krasnoselsky district of St. Petersburg in 2008–2014 varied from 1359.6 to 1768.5 per 1000 children attending these institutions. In general educational schools the morbidity index in the aforesaid period were 422.6–521.6 (p < 0.001). From 49.3 to 55.4% of children were vaccinated against influenza; from 3600 to 4700 children annually stayed unimmunized due to medical contraindications and parents’ refusals from prophylactic immunization. The research objective is clinical-epidemiological substantiation of effectiveness of application of Echinacea botanical medicine to reduce the ARVI morbidity and the rate of complications after the disease among children attending educational institutions. As a result of the research it was established that the ARVI morbidity index in the group of the children who received the Echinacea preparation was 76.8; in the comparison group it was 94.2 per 100 people (p < 0.01; RR = 0.80; CI = 0.7–0.9). The rate of complications (bronchitis, otitis, adenoiditis, pneumonia, sinusitis) among the children who received the preparation was 2–4.8 times lower.

About the authors

L. R. Ishrefova

Network of Versatile Clinics “BaltZdrav”;
St. Petersburg Pasteur Institute

Author for correspondence.
Email: larissa.r@mail.ru

Pediatrician;

PhD Candidate, Laboratory of Epidemiology,

197101, St. Petersburg, Mira str., 14,

Россия

L. V. Lyalina

St. Petersburg Pasteur Institute

Email: fake@neicon.ru

PhD, MD (Medicine), Professor, Head of the Laboratory of Epidemiology,

St. Petersburg

Россия

D. A. Lioznov

Pavlov First St. Petersburg State Medical University;
St. Petersburg Pasteur Institute

Email: fake@neicon.ru

PhD, MD (Medicine), Head of the Department of Infectious Diseases and Epidemiology;

Leading Researcher, Laboratory of Viral Hepatitis,

St. Petersburg

Россия

O. V. Matochkina

SPb SBHI Municipal Polyclinic No. 91

Email: fake@neicon.ru

Pediatrician, Children’s Outpatient Department No. 60,

St. Petersburg

Россия

T. Yu. Davydova

SPb SBHI Municipal Polyclinic No. 91

Email: fake@neicon.ru

Pediatrician, Children’s Outpatient Department No. 27,

St. Petersburg

Россия

L. E. Zakharova

SPb SBHI Municipal Polyclinic No. 91

Email: fake@neicon.ru

Pediatrician, Head of the Preschool and School Department, Children’s Outpatient Department No. 60,

St. Petersburg

Россия

References

  1. Гагаринова В.М., Брахотская О.В., Бойков Ю.А., Мухленов А.Г., Ишрефова Л.Р., Щербина А.Н. Эффективность препарата Мидэл в системе неспецифической защиты детей 3–14 лет от вирусных инфекций // Эпидемиология и вакцинопрофилактика. 2003. Т. 4, № 11. С. 34–36. [Gagarinova V.M., Brakhotskaya O.V., Boikov Yu.A., Mukhlenov A.G., Ishrefova L.R., Shcherbina A.N. The effectiveness of the drug Midel in the system of nonspecific protection of children 3–14 years of age from viral infections. Epidemiologiya i vaktsinoprofilaktika = Epidemiology and Vaccinal Prevention, 2003, vol. 4, no. 11, pp. 34–36. (In Russ.)]
  2. Зайцева О.В. Рекуррентные респираторные инфекции: можно ли предупредить? // Педиатрия. 2015. Т. 94, № 2. С. 185–192. [Zaytseva O.V. Recurrent respiratory infections: is it possible to prevent them? Pediatriya = Pediatry, 2015, vol. 94, no. 2, pp. 185–192. (In Russ.)]
  3. Зуева Л.П., Яфаев Р.Х., Еремин С.Р. Эпидемиологическая диагностика. СПб.: ГОУВПО СПб ГМА им. И.И. Мечникова Минздрава России, 2003. 264 с. [Zueva L.P., Yafaev R.H., Eremin S.P. Epidemiologicheskaya diagnostika [Epidemiological diagnostics]. St. Petersburg: Mechnikov State Medical Academy, 2003. 264 p.]
  4. Ишрефова Л.Р., Гагаринова В.М. Неспецифическая профилактика вирусных инфекций у часто болеющих детей // Цитокины и воспаление. 2005. Т. 4, № 3. С. 136. [Ishrefova L.R., Gagarinova V.M. Nonpecifical prevention of viral infections in frequently ailing children. Tsitokiny i vospalenie = Cytokines and Inflammation, 2005, vol. 4, no. 3, p. 136. (In Russ.)]
  5. Казюкова Т.В., Панкратов И.В., Самсыгина Г.А., Алеев А.С., Дудина Т.А. Возможности семейной профилактики гриппа и острых респираторных вирусных инфекций // Педиатрия. 2010. Т. 89, № 6. С. 117–122. [Kazyukova T.V., Pankratov I.V., Samsygina G.A., Aleev A.S., Dudina T.A. Family prevention of influenza and acute respiratory viral infections. Pediatriya = Pediatry, 2010, vol. 89, no. 6, pp. 117–122. (In Russ.)]
  6. Нисевич Л.Л., Волков К.С., Алексеева А.А., Томилова А.Ю., Баранник В.А., Эфендиева К.Е. Подходы к терапии острых респираторных инфекций и гриппа при сезонном увеличении заболеваемости // Вопросы современной педиатрии. 2015. Т. 14, № 1. С. 64–69. [Nisevich L.L., Volkov K.S., Alekseeva A.A., Tomilova A.Yu, Barannik V.A., Efendieva K.Ye. Approaches to the treatment of acute respiratory infections and influenza during the seasonal increase in the incidence of diseases. Voprosy sovremennoi pediatrii = Current Pediatrics, 2015, vol. 14, no. 1, pp. 64–69. (In Russ.)]
  7. Ревякина В.А. Перспективы использования растительных иммуномодуляторов в профилактике и терапии респираторных инфекций у детей // Инфекционные болезни. 2013. Т. 11, № 1. С. 93–96. [Revyakina V.A. Perspectives in using herbal immunomodulators for prevention and therapy of respiratory infections in children. Infektsionnye bolezni = Infectious Diseases, 2013, vol. 11, no. 1, pp. 93–96. (In Russ.)]
  8. Тутельян В.А., Суханов Б.П. Биологически активные добавки к пище: современные подходы к обеспечению качества и безопасности // Вопросы питания. 2008. Т. 77, № 4. С. 5–15. [Tutelian V.A., Sukhanov B.P. Biologically active food supplements: current approaches to quality assurance and safety. Voprosy pitaniya = Nutrition, 2008, vol. 77, no. 4, pp. 5–15. (In Russ.)]
  9. Ghaemi A., Soleimanjahi H., Gill P., Arefian E., Soudi S., Hassan Z. Echinacea purpurea polysaccharide reduces the latency rate in Herpes simplex virus type-1 infections. Intervirology, 2009, vol. 52, no. 1, pp. 29–34. doi: 10.1159/000212988
  10. Groom S.N., Johns T., Oldfield P.R. The potency of immunomodulatory herbs may be primarily dependent upon macrophage activation. J. Med. Food, 2007, vol. 10, no. 1, pp. 73–79. doi: 10.1089/jmf.2006.233
  11. Hall H., Fahlman M.M., Engels H.J. Echinacea purpurea and mucosal immunity. Int. J. Sports Med., 2007, vol. 28, no. 9, pp. 792–797. doi: 10.1055/s-2007-964895
  12. Linde K., Barrett B., Woelkart K., Bauer R., Melchart D. Echinacea for preventing and treating the common cold. Cochrane Database Syst. Rev., 2006, 1: CD000530. doi: 10.1002/14651858.CD000530.pub2
  13. Pleschka S., Stein M., Schoop R., Hudson J.B. Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV). Virol. J., 2009, vol. 13, no. 6, p. 197. doi: 10.1186/1743-422X-6-197

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2016 Ishrefova L.R., Lyalina L.V., Lioznov D.A., Matochkina O.V., Davydova T.Y., Zakharova L.E.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 64788 от 02.02.2016.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies