Russian Journal of Infection and ImmunityRussian Journal of Infection and Immunity2220-76192313-7398SPb RAACI40510.15789/2220-7619-2016-2-184-188ARGUMENTATION OF ACUTE RESPIRATORY VIRAL INFECTIONS NONSPECIFIC PREVENTION IN GROUPS OF CHILDRENIshrefovaL. R.<p>Pediatrician;</p><p>PhD Candidate, Laboratory of Epidemiology,</p><p>197101, St. Petersburg, Mira str., 14,</p>larissa.r@mail.ruLyalinaL. V.<p>PhD, MD (Medicine), Professor, Head of the Laboratory of Epidemiology,</p><p>St. Petersburg</p>fake@neicon.ruLioznovD. A.<p>PhD, MD (Medicine), Head of the Department of Infectious Diseases and Epidemiology;</p><p>Leading Researcher, Laboratory of Viral Hepatitis,</p><p>St. Petersburg</p>fake@neicon.ruMatochkinaO. V.<p>Pediatrician, Children’s Outpatient Department No. 60,</p><p>St. Petersburg</p>fake@neicon.ruDavydovaT. Yu.<p>Pediatrician, Children’s Outpatient Department No. 27,</p><p>St. Petersburg</p>fake@neicon.ruZakharovaL. E.<p>Pediatrician, Head of the Preschool and School Department, Children’s Outpatient Department No. 60,</p><p>St. Petersburg</p>fake@neicon.ruNetwork of Versatile Clinics “BaltZdrav”St. Petersburg Pasteur InstitutePavlov First St. Petersburg State Medical UniversitySPb SBHI Municipal Polyclinic No. 9125062016621841882506201625062016Copyright © 2016, Ishrefova L.R., Lyalina L.V., Lioznov D.A., Matochkina O.V., Davydova T.Y., Zakharova L.E.2016Acute respiratory viral infections (ARVI) and influenza are among the topical problems of healthcare. The children’s morbidity index in preschool educational institutions in Krasnoselsky district of St. Petersburg in 2008–2014 varied from 1359.6 to 1768.5 per 1000 children attending these institutions. In general educational schools the morbidity index in the aforesaid period were 422.6–521.6 (p 0.001). From 49.3 to 55.4% of children were vaccinated against influenza; from 3600 to 4700 children annually stayed unimmunized due to medical contraindications and parents’ refusals from prophylactic immunization. The research objective is clinical-epidemiological substantiation of effectiveness of application of Echinacea botanical medicine to reduce the ARVI morbidity and the rate of complications after the disease among children attending educational institutions. As a result of the research it was established that the ARVI morbidity index in the group of the children who received the Echinacea preparation was 76.8; in the comparison group it was 94.2 per 100 people (p 0.01; RR = 0.80; CI = 0.7–0.9). 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