Email this article DURATION OF POSTVACCINAL IMMUNITY AGAINST HEPATITIS B IN HEALTH CARE WORKERS IN ST. PETERSBURG
- Authors: Kalinina Z.P.1, Dar’ina M.G.1, Movchan K.N.1, Mamicheva O.Y.2, Gagarkina I.B.3, Averina T.Y.3, Balabash O.A.3, Yefimova L.I.3, Potemkina I.V.3
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Affiliations:
- 198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center. North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
- North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
- 198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
- Issue: Vol 5, No 1 (2015)
- Pages: 89-92
- Section: SHORT COMMUNICATIONS
- Submitted: 21.04.2015
- Accepted: 21.04.2015
- Published: 21.04.2015
- URL: https://iimmun.ru/iimm/article/view/279
- DOI: https://doi.org/10.15789/2220-7619-2015-1-
- ID: 279
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Abstract
Immunization against hepatitis В is the most effective method of preventing this disease. Study of quantitative characteristics of postvaccinal immunity against viral hepatitis В in 214 health care workers from different institutions of St. Petersburg has shown that HBV vaccine provides a long term immunity in 80% of cases with the absence of manifest forms of the disease. The duration of circulation of high titers of antibodies depended on the age of people when vaccination was provided. The highest level of immunity was observed in people vaccinated before the age of 30 years (84,0–90,6%). Reduction of immunity level in vaccinated health care workers after 5 years from the date of vaccination requires revaccination against viral hepatitis B after pre-vaccination screening.
About the authors
Z. P. Kalinina
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
Author for correspondence.
Email: KalininaZ@miac.zdrav.spb.ru
PhD (Medicine), Epidemiologist of Sector for Clinical Epidemiology of the Organizational-Methodical Department
for Monitoring the Quality of Medical Practice St. Petersburg Мedical Informational Analytical Center; Associate Professor of the Department of Epidemiology, Parasitology and Dezinfektologii North-Western State medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation;
M. G. Dar’ina
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
Email: fake@neicon.ru
PhD (Medicine), Head of the Epidemiologist Sector of Clinical Epidemiology of Organizational-Methodical Department for Monitoring the Quality of Medical Practice St. Petersburg Medical Informational Analytical Center; Assistant of Chair Epidemiology, Parasitology and Dezinfektologii North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation;
K. N. Movchan
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
Email: fake@neicon.ru
PhD (Medicine), Head of the Organizational- Methodical Department for Monitoring the Quality of Medical Practice St. Petersburg Medical Informational Analytical Center; Professor of Chair Surgery named after N.D. Monastirskyi North- Western State Medical University named after I.I. Mechnikov,
St. Petersburg, Russian Federation;
O. Yu. Mamicheva
North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation
Email: fake@neicon.ru
PhD Candidate North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation;
I. B. Gagarkina
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
Email: fake@neicon.ru
Epidemiologist, Expert of St. Petersburg Medical Informational Analytical Center, St. Petersburg, Russian Federation;
T. Ya. Averina
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
Email: fake@neicon.ru
Epidemiologist, Expert of St. Petersburg Medical Informational Analytical Center, St. Petersburg, Russian Federation;
O. A. Balabash
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
Email: fake@neicon.ru
Epidemiologist, Expert of St. Petersburg Medical Informational Analytical Center, St. Petersburg, Russian Federation;
L. I. Yefimova
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
Email: fake@neicon.ru
Epidemiologist, Expert of St. Petersburg Medical Informational Analytical Center, St. Petersburg, Russian Federation;
I. V. Potemkina
198095, Russian Federation, St. Petersburg, str. Shkapina, 30, letter A, St. Petersburg Мedical Informational-Analytical Center.
Email: fake@neicon.ru
Epidemiologist, Expert of St. Petersburg Medical Informational Analytical Center, St. Petersburg, Russian Federation.
References
- Вакцины и вакцинация: национальное руководство / Под ред. В.В. Зверева, Б.Ф. Семенова, Р.М. Хаитова. М.: ГЭОТАР-Медиа, 2011. 485 с. [Vaktsiny i vaktsinatsiya: natsional’noe rukovodstvo [Vaccines and vaccination: the national guide / Eds. Zverev V.V., Smirnov B.F., Khaitov R.M.]. Moscow: GEOTAR-Меdia, 2011, 485 p.
- Калинина З.П., Мовчан К.Н., Дарьина М.Г., Техова И.Г., Захватова А.С., Мамичева О.Ю., Русакевич К.И. Вопросы профилактики гемоконтактных гепатитов у медицинских работников в стационарах Санкт-Петербурга // Фундаментальные исследования. 2014. No 10 (5). С. 882–887. [Kalinina Z.P., Movchan K.N., Darina M.G., Tekhova I.G., Zakhvatova A.S., Mamicheva O.Y., Rusakevich K.I. To the prevention of blood-borne hepatitis in health workers in hospitals of St. Petersburg. Fundamental’nye issledovaniya = Fundamental Research, 2014, no. 5, pp. 882–887. (In Russ.)]
- Калинина З.П., Дарьина М.Г., Захватова А.С., Мамичева О.Ю. О профилактике инфекционных заболеваний медицинских работников стационаров // Проблемы медицинской микологии. 2014. Т. 16, No 2. С. 80. [Kalinina Z.P., Dar’ina M.G., Zahvatova A.S., Mamicheva O.Ya. About the prevention of infectious diseases, health care workers of hospitals. Problemy meditsinskoi mikologii = Problems of Medical Mycology, 2014, vol. 16, no. 2, p. 80. (In Russ.)]
- Тайц Б.М., Платошина О.В., Чернова Л.К., Ахтырская Н.А., Андреева Н.В., Вашукова С.С., Крыга Л.Н. Вакцинопрофилактика вирусного гепатита В // Актуальные проблемы вакцинопрофилактики. СПб.: Изд-во «ССЗ», 1967. С. 128–129. [Taits B.M., Platoshina O.V., Chernova L.K., Achtirskaya N.A., Andreyeva N.V., Vashukova S.S., Kryga L.N. Vaktsinoprofilaktika virusnogo gepatita B. [Hepatitis B Immunization]. Aktual’nye problemy vaktsinoprofilaktiki = Actual Problems of Vaccinal. St. Petersburg: The Publishing House of «GCC», 1967, pp. 128–129.]
- Фельдблюм И.В. Вакцинопрофилактика гепатита В в России: опыт использования отечественных медицинских иммунобиологических препаратов // Эпидемиология и вакцинопрофилактика. 2012. No 4 (65). С. 61–65. [Fel’dblyum I.V. Hepatitis B vaccines in Russia: experience of the use of domestic medical biological immunity preparations. Epidemiologiya i vaktsinoprofilaktika = Epidemiology and Vaccines, 2012, no. 4 (65), pp. 61–65. (In Russ.)]
- Шахгильдян И.В., Михайлов М.И., Онищенко Г.Г. Парентеральные вирусные гепатиты (эпидемиология, диагностика, профилактика). М.: ГОУ ВУНМЦ МЗ РФ, 2003. 384 c. [Shakhgil’dyan I.V., Mikhailov M.I., Onishchenko G.G. Parenteral’nye virusnye gepatity (epidemiologiya, diagnostika, profilaktika) [Parenteral viral hepatitis (epidemiology, diagnostics, prevention)]. Moscow: GO VUNMC Ministry of Health of the Russian Federation, 2003, p. 384.]
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