Email this article THE STUDY OF VIRUSES REPRODUCTION IN CELL CULTURES BY THE METHOD OF MATHEMATICAL MODELING
- Authors: Kontarov N.A.1, Grishunina S.A.2, Balaev N.V.1, Yuminova N.V.1, Zverev V.V.1
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Affiliations:
- Research Institute of Vaccines and Sera of I.I. Mechnikov RAMS, Moscow
- Lomonosov Moscow State University, Moscow
- Issue: Vol 3, No 4 (2013)
- Pages: 376-378
- Section: SHORT COMMUNICATIONS
- URL: https://iimmun.ru/iimm/article/view/150
- DOI: https://doi.org/10.15789/2220-7619-2013-4-376-378
- ID: 150
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Abstract
Abstract. In the study the mathematical analysis of viruses reproduction in cell culture using the Marchuk’ mathematical model to predict reproduction of virus in one or another cell cultures has been conducted. The obtained theoretical results are corresponded to the experimental data on reproduction of rubella virus in cell cultures RK-13 and BHK-21. The sum of theoretical and experimental results can be used to select the optimal cell cultures for virus cumulation.
About the authors
N. A. Kontarov
Research Institute of Vaccines and Sera of I.I. Mechnikov RAMS, Moscow
Author for correspondence.
Email: kontarov@mail.ru
PhD (Biology), Senior Researcher, Laboratory of the Children’s Viral Infections, Department of Virology
127549, Russian Federation, Moscow, Muranovskaya str., 6, 218
Russian FederationS. A. Grishunina
Lomonosov Moscow State University, Moscow
Email: kontarov@mail.ru
4th year student, Faculty of Mechanics and Mathematics Russian Federation
N. V. Balaev
Research Institute of Vaccines and Sera of I.I. Mechnikov RAMS, Moscow
Email: kontarov@mail.ru
PhD (Biology), Researcher, Laboratory of childhood viral infections, Department of Virology Russian Federation
N. V. Yuminova
Research Institute of Vaccines and Sera of I.I. Mechnikov RAMS, Moscow
Email: kontarov@mail.ru
PhD, MD (Biology), Deputy Director of Research Russian Federation
V. V. Zverev
Research Institute of Vaccines and Sera of I.I. Mechnikov RAMS, Moscow
Email: kontarov@mail.ru
PhD, MD (Biology), Professor, Full Member of the Russian Academy of Medical Sciences, Director Russian Federation
References
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