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Abstract. Presence of specific antibodies to H. pylori and to its Cag A toxin was studied in 1917 persons, including 860 children and 1057 adults, in Pasteur Research Institute of Epidemiology and Microbiology, St. Petersburg, Russia. The studied group was presented by the subjectively healthy individuals and blood donors living in St. Petersburg. The growth and stabilization of serological positive rates to H. pilory at high level, as well as increasing the proportion of CagA-positive infection among children and adults in St. Petersburg in 2007–2011 have been established. There are 3 age risk groups of H. pylori infection among children population: 4–5 years, 7–8 years and 14–15 years. The shift of the maximum H. pylori seropositivity rates from age group of 30–39 years in 2007 to age group 40–49 years in 2011 was detected.

About the authors

A. V. Svarval

ФБУН НИИ эпидемиологии и микробиологии имени Пастера, Санкт-Петербург

Author for correspondence.

научный сотрудник лаборатории иммунологии

197101, Санкт-Петербург, ул. Мира, 14

Russian Federation

R. S. Ferman

ФБУН НИИ эпидемиологии и микробиологии имени Пастера, Санкт-Петербург

Russian Federation

A. B. Zhebrun

ФБУН НИИ эпидемиологии и микробиологии имени Пастера, Санкт-Петербург

Russian Federation


  1. Инфекционная заболеваемость в Северо-Западном федеральном округе России. Закономерности и особенности эпидемического процесса в современный период: Аналитич. обзор. — СПб.: Феникс, 2007. — С. 89–98.
  2. Основные показатели состояния здоровья населения, ресурсы и деятельность учреждений здравоохранения Санкт-Петербурга в 1996–2003 г. // Под ред. И.А. Красильникова. — СПб., 2004. — 480 с.
  3. Сварваль А.В., Ферман Р.С., Жебрун А.Б. Распространенность инфекции Helicobacter pylori среди населения Северо-Западного федерального округа Российской Федерации // ЖМЭИ. — 2011. — № 4. — С. 84–88.
  4. Cervantes D.T., Fischbach L.A., Goodman K.J., Phillips C.V., Chen S., Broussard C.S. Exposure to Helicobacter pylori-positive siblings and persistence of Helicobacter pylori infection in early childhood // J. Pediatr. Gastroenterol. Nutr. — 2010. — Vol. 50, Iss.5. — P. 481–485.
  5. Dattoli V.C., Veiga R.V., da Cunha S.S., Pontes-de-Carvalho L.C., Barreto M.L., Alcantara-Neves N.M. Seroprevalence and potential risk factors for Helicobacter pylori infection in Brazilian children // Helicobacter. — 2010. — Vol. 15. — P. 273–278.
  6. Goh K.L., Chan W.K., Shiota S., Yamaoka Y. Epidemiology of Helicobacter pylori Infection and Public Health Implications // Helicobacter. — 2011. — Vol. 16, Suppl. 1. — P. 1–9.
  7. Li Z., Zou D., Ma X., Chen J., Shi X., Gong Y., Man X., Gao L., Zhao Y., Wang R., Yan X., Dent J., Sung J.J., Wernersson B., Johansson S., Liu W., He J. Epidemiology of peptic ulcer disease: endoscopic results of the systematic investigation of gastrointestinal disease in China // Am. J. Gastroenterol. — 2010. — Vol. 105, N 12. — P. 2570–2577.
  8. Malfertheiner P., Megraud F., O’Morain C.A., Atherton J., Axon A.T., Bazzoli F., Gensini G.F., Gisbert J.P., Graham D.Y., Rokkas T., El-Omar E.M., Kuipers E.J.; European Helicobacter Study Group. Management of Helicobacter pylori infectiondthe Maastricht IV/Florence Consensus Report // Gut. — 2012. — Vol. 61. — P. 646–664.
  9. Muhsen K., Athamna A., Bialik A., Alpert G., Cohen D. Presence of Helicobacter pylori in a sibling is associated with a long-term increased risk of H. pylori infection in Israeli Arab children // Helicobacter. — 2010. — Vol. 15. — P. 108–113.
  10. Nam S.Y., Choi I.J., Ryu K.H., Kim B.C., Kim C.G., Nam B.H. Effect of Helicobacter pylori infection and its eradication on reflux esophagitis and reflux symptoms // Am. J. Gastroenterol. — 2010. — Vol. 105, N 10. — P. 2153–2162.
  11. Nguyen T.L., Uchida T., Tsukamoto Y., Trinh D.T., Ta L., Mai B.H., Le S.H., Thai K.D., Ho D.D., Hoang H.H., Matsuhisa T., Okimoto T., Kodama M., Mura kami K., Fujioka T., Yamaoka Y., Moriyama M. Helicobacter pylori infection and gastroduodenal diseases in Vietnam: a cross-sectional, hospital-based study // BMC Gastroenterol. — 2010. — Vol. 10. — P. 114.
  12. Ozdil K., Sahin A., Kahraman R., Yuzbasioglu B., Demirdag H., Calhan T., Yilmaz M.S., Sokmen H.M. Current prevalence of intestinal metaplasia and Helicobacter pylori infection in dyspeptic adult patients from Turkey // Hepatogastroenterology. — 2010. — Vol. 57, N 104. — P. 1563–1566.
  13. Pandeya N., Whiteman D.C. Prevalence and determinants of Helicobacter pylori sero-positivity in the Australian adult community // J. Gastroenterol. Hepatol. — 2011. — Vol. 26, N 8. — P. 1283–1289.
  14. Sonnenberg A., Lash R.H., Genta R.M. A national study of Helicobactor pylori infection in gastric biopsy specimens // Gastroenterology. — 2010. — Vol. 139, N 6. — P. 1894–1901.

Copyright (c) 2014 Svarval A.V., Ferman R.S., Zhebrun A.B.

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