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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Infection and Immunity</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Infection and Immunity</journal-title><trans-title-group xml:lang="ru"><trans-title>Инфекция и иммунитет</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2220-7619</issn><issn publication-format="electronic">2313-7398</issn><publisher><publisher-name xml:lang="en">SPb RAACI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">112</article-id><article-id pub-id-type="doi">10.15789/2220-7619-2012-4-741-746</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">STUDY OF THE DYNAMIC OF HELICOBACTER PYLORI INFECTION PREVALENCE IN DIFFERENT AGE GROUPS OF ST. PETERSBURG POPULATION IN 2007-2011</article-title><trans-title-group xml:lang="ru"><trans-title>ИЗУЧЕНИЕ ДИНАМИКИ ПРЕВАЛЕНТНОСТИ ИНФЕКЦИИ, ОБУСЛОВЛЕННОЙ HELICOBACTER PYLORI, СРЕДИ РАЗЛИЧНЫХ ВОЗРАСТНЫХ ГРУПП НАСЕЛЕНИЯ САНКТ-ПЕТЕРБУРГА В 2007–2011 ГОДАХ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Svarval</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Сварваль</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>научный сотрудник лаборатории иммунологии</p><p>197101, Санкт-Петербург, ул. Мира, 14</p></bio><email>laborimmun@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ferman</surname><given-names>R. S.</given-names></name><name xml:lang="ru"><surname>Ферман</surname><given-names>Р. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>laborimmun@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zhebrun</surname><given-names>A. B.</given-names></name><name xml:lang="ru"><surname>Жебрун</surname><given-names>А. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>laborimmun@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ФБУН НИИ эпидемиологии и микробиологии имени Пастера, Санкт-Петербург</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-07-04" publication-format="electronic"><day>04</day><month>07</month><year>2012</year></pub-date><volume>2</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>741</fpage><lpage>746</lpage><history><date date-type="received" iso-8601-date="2014-07-04"><day>04</day><month>07</month><year>2014</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Svarval A.V., Ferman R.S., Zhebrun A.B.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, Сварваль А.В., Ферман Р.С., Жебрун А.Б.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Svarval A.V., Ferman R.S., Zhebrun A.B.</copyright-holder><copyright-holder xml:lang="ru">Сварваль А.В., Ферман Р.С., Жебрун А.Б.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://iimmun.ru/iimm/article/view/112">https://iimmun.ru/iimm/article/view/112</self-uri><abstract xml:lang="en"><p><bold>Abstract.</bold> Presence of specific antibodies to H. pylori and to its Cag A toxin was studied in 1917 persons, including 860 children and 1057 adults, in Pasteur Research Institute of Epidemiology and Microbiology, St. Petersburg, Russia. The studied group was presented by the subjectively healthy individuals and blood donors living in St. Petersburg. The growth and stabilization of serological positive rates to H. pilory at high level, as well as increasing the proportion of CagA-positive infection among children and adults in St. Petersburg in 2007–2011 have been established. There are 3 age risk groups of H. pylori infection among children population: 4–5 years, 7–8 years and 14–15 years. The shift of the maximum H. pylori seropositivity rates from age group of 30–39 years in 2007 to age group 40–49 years in 2011 was detected.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Резюме.</bold>На базе ФБУН НИИ эпидемиологии и микробиологии имени Пастера обследовано 1917 человек, в том числе 860 детей и 1057 взрослых, проживающих в Санкт-Петербурге, субъективно здоровых лиц и доноров крови. У всех определены титры специфических антител к H. pylori и его токсину CagA. При изучении динамики серопозитивности к H. pylori среди детского и взрослого населения Санкт-Петербурга за 2007–2011 гг. выявлен рост и стабилизация значений на достаточно высоком уровне, а также увеличение доли CagA-позитивной инфекции в ее общей структуре. Выявлен волнообразный характер распространения данной инфекции среди детской популяции с подъемами в 4–5 лет, 7–8 лет и 14–15 лет. При рассмотрении различий в серопревалентности к инфекции, обусловленной H. pylori, среди взрослых отмечено смещение максимальных значений серопозитивности с возрастной группы 30–39 лет в 2007 г. на возрастную группу 40–49 лет в 2011 г.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Helicobacter pylori</kwd><kwd>H. pylori infection</kwd><kwd>IgG to H. pylori</kwd><kwd>antibodies to H. pylori CagA</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Helicobacter pylori</kwd><kwd>инфекция</kwd><kwd>обусловленная H. pylori</kwd><kwd>IgG к H. pylori</kwd><kwd>антитела к CagA H. pylori</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1.	Инфекционная заболеваемость в Северо-Западном федеральном округе России. Закономерности и особенности эпидемического процесса в современный период: Аналитич. обзор. — СПб.: Феникс, 2007. — С. 89–98.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2.	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