COVID-19: обновленный взгляд
- Авторы: Исихак Ф.А.1, Хамад М.А.1, Мустафа Н.Г.1
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Учреждения:
- Университет Мосула
- Выпуск: Том 10, № 2 (2020)
- Страницы: 247-258
- Раздел: ОБЗОРЫ
- Дата подачи: 04.04.2020
- Дата принятия к публикации: 06.04.2020
- Дата публикации: 14.04.2020
- URL: https://iimmun.ru/iimm/article/view/1443
- DOI: https://doi.org/10.15789/2220-7619-CAU-1443
- ID: 1443
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Аннотация
COVID-19 является зоонозным заболеванием, для которого обнаружен более высокий уровень передачи у человека. Среди всех РНК-содержащих вирусов коронавирусы имеют наибольший размер генома (28–33 п.о.), представленный положительно-полярной нитью РНК. В частности, их геном содержит 5′-конец, транслируемые мРНК, соответствующие ключевым белкам; репликазу, белок spike (шип), белки оболочки, нуклеокапсид и 3′-конец (поли-A хвост). Этот высококонтагиозный вирус может влиять на иммунную систему на ранней стадии инфекции, из-за чего симптомы заболевания проявляются очень быстро. Важно, что до сих пор отсутствует эффективная стратегия по ограничению этого заболевания. Исходя из этого, ученые всего мира в гонке со временем заняты поиском вакцин или методов лечения COVID-19, что требует более глубокого понимания течения заболевания.
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Об авторах
Ф. А. Исихак
Университет Мосула
Email: fanar1976@yahoo.com
ORCID iD: 0000-0002-6409-3969
доцент кафедры микробиологии Колледжа ветеринарной медицины
г. Мосул
ИракМ. А. Хамад
Университет Мосула
Автор, ответственный за переписку.
Email: mahmah1073@gmail.com
ORCID iD: 0000-0001-9278-5391
Мохаммад А. Хамад – доцент кафедры микробиологии Колледжа ветеринарной медицины
г. Мосул, ул. Аль-Маджмоа
Тел.: +964 77 28214770
Н. Г. Мустафа
Университет Мосула
Email: nashaat_ghalib@yahoo.com
ORCID iD: 0000-0002-8351-1230
профессор, зав. кафедрой физиологии, биохимии и фармакологии Колледжа ветеринарной медицины
г. Мосул
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