VIRAL HEPATITIS E DIAGNOSTICS

Cover Page


Cite item

Full Text

Abstract

Abstract. The results of clinical and epidemiological studies conducted in the M.P. Chumakov’ Research Institute of Poliomyelitis and Viral Encephalitis and in the different research institutions of the world have been summarized in the current article. Data on etiology, pathogenesis, clinical symptoms, epidemiology and prevention of hepatitis E are presented. Increasing of significance of this infection for health care system in Russia is emphasized . The actual problems of hepatitis E (autochthonic hepatitis E, hepatitis E as zoonosis, chronic hepatitis E) are discussed.

About the authors

E. Yu. Malinnikova

Chumakov Institute of Poliomyelitis and Viral Encephalitis of Russian Academy of Medical Sciences, Moscow region

Author for correspondence.
Email: malinacgb@mail.ru

PhD (Medicine), Leading Researcher, Department of viral hepatitis

142782, Russian Federation, Moscow region, Leninsky district, village countryside Institute of Poliomyelitis, 27 km Kiev highway

Russian Federation

L. Yu. Ilchenko

Chumakov Institute of Poliomyelitis and Viral Encephalitis of Russian Academy of Medical Sciences, Moscow region

Email: malinacgb@mail.ru
PhD, MD (Medicine), Professor, Head of the Department of viral hepatitis Russian Federation

M. I. Mikhaylov

Chumakov Institute of Poliomyelitis and Viral Encephalitis of Russian Academy of Medical Sciences, Moscow region

Email: malinacgb@mail.ru
PhD, MD (Medicine), Professor, Corresponding Member of the Russian Academy of Medical Sciences, Director Russian Federation

References

  1. Михайлов М.И., Малинникова Е.Ю., Кюрегян К.К., Исаева О.Е., Гордейчук И.В., Солонин С.А., Зайцев О.В., Заботина Е.Е., Манина Т.А., Лисицина Е.В., Душина И.Ф., Штурмина С.М., Краснов В.П., Груздев К.Н., Брызгалов С.П., Лисицин Е.А. Групповая заболеваемость гепатитом Е в г. Коврове Владимирской области (Предварительное сообщение) // Медицинская вирусология. — 2009. — Т. 26. — C. 239–245. Mikhaylov M.I., Malinnikova E.Yu., Kyuregyan K.K., Isaeva O.E., Gordeychuk I.V., Solonin S.A., Zaytsev O.V., Zabotina E.E., Manina T.A., Lisitsina E.V., Dushina I.F., Shturmina S.M., Krasnov V.P., Gruzdev K.N., Bryzgalov S.P., Lisitsin E.A. Gruppovaya zabolevaemost` gepatitom E v g. Kovrove Vladimirskoy oblasti (Predvaritel`noe soobshchenie) [Group incidence of hepatitis E in Kovrov Vladimir region (preliminary report)]. Meditsinskaya virusologiya — Medical Virology, 2009, vol. 26, pp. 239–245.
  2. Оглезнева Е.Е., Землянский О.А., Пономаренко Т.Н., Шинкаренко Н.Н. Эпидемиологическая характеристика острых вирусных гепатитов в Белгородской области // Инфекция и иммунитет. — 2012. — Т. 2, № 1–2: Итоги и перспективы обеспечения эпидемиологического благополучия населения Российской Федерации: материалы X съезда Всерос. науч.-практ. о-ва эпидемиологов, микробиологов и паразитологов. – C. 454. Oglezneva E.E., Zemlyanskiy O.A., Ponomarenko T.N., Shinkarenko N.N. Epidemiologicheskaya kharakteristika ostrykh virusnykh gepatitov v Belgorodskoy oblasti [Epidemiological characteristics of acute viral hepatitis in the Belgorod region]. Materialy X s”ezda Vseros. nauch.-prakt. o-va epidemiologov, mikrobiologov i parazitologov “Itogi i perspektivy obespecheniya epidemiologicheskogo blagopoluchiya naseleniya Rossiyskoy Federatsii” [Proceedings of the X congress of the All-Russian Scientific Society epidemiologists, microbiologists and parasitologists. Moscow, 12–13 April 2012]. Infektsiya i immunitet — Infection and Immunity, 2012, vol. 2, no. 1–2, pp. 454.
  3. Aggarwal R. Clinical presentation of hepatitis E. Virus Res., 2011, vol. 161 (1), pp. 15–22.
  4. Balayan M.S., Andjaparidze A.G., Savinskaya S.S., Ketiladze E.S., Braginsky D.M., Savinov A.P., Poleschuk V.F. Evidence for a virus non-A, non-B hepatitis transmitted via the fecal-oral route. Intervirology, 1983, vol. 20, no. 1, pp. 23–31.
  5. Banks M., Bendall R., Grierson S., Heath G., Mitchell J., Dalton H. Human and porcine hepatitis E virus strains. United Kingdom Emerg. Infect. Dis, 2004, vol. 10, no. 5, pp. 953–955.
  6. Colson P., Borentain P., Queyriaux B., Kaba M., Moal V., Gallian P., Heyries L., Raoult D., Gerolami R. Pig liver sausage as a source of hepatitis E virus transmission to humans. J. Infect. Dis., 2010, vol. 202, no. 6, pp. 825–834.
  7. Dalton H.R. Hepatitis: hepatitis E and decompensated chronic liver disease. Nat. Rev. Gastroenterol. Hepatol., 2012, vol. 24, no. 8, pp. 121.
  8. Drobeniuc J., Favorov M.O., Shapiro C.N., Bell B.P., Mast E.E., Dadu A., Culver D., Iarovoi P., Robertson B.H., Margolis H.S. Hepatitis E virus antibody prevalence among persons who work with swine. J. Infect. Dis., 2001, vol. 184, no. 12, pp. 1594–1597.
  9. Kamar N., Rostaing L., Abravanel F., Garrouste C., Lhomme S., Esposito L., Basse G., Cointault O., Ribes D., Nogier M.B., Alric L., Peron J.M., Izopet J. Ribavirin therapy inhibits viral replication in patients with chronic hepatitis E virus infection. Gastroenterology, 2010, no. 139, pp. 1612–1618.
  10. Kamar N., Rostaing L., Abravanel F., Garrouste C., Esposito L., Cardeau-Desangles I., Mansuy J.M., Selves J., Peron J.M., Otal P., Muscari F., Izopet J. Pegylated interferon-alpha for treating chronic hepatitis E virus infection after liver transplantation. Clin. Infect. Dis., 2010, no. 50, pp. e30–e33.
  11. Kamar N., Garrouste C., Haagsma E.B., Garrigue V., Pischke S., Chauvet C., Dumortier J., Cannesson A., Cassuto-Viguier E., Thervet E., Conti F., Lebray P., Dalton H.R., Santella R., Kanaan N., Essig M., Mousson C., Radenne S., Roque-Afonso A.M., Izopet J., Rostaing L. Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants. Gastroenterology, 2011, no. 140, pp. 1481–1489.
  12. Kamar N., Bendall R., Legrand-Abravanel F., Xia N.S., Ijaz S., Izopet J., Dalton H.R. Hepatitis E. Lancet, 2012, vol. 379, no. 9835, pp. 2477–2488.
  13. Marcus E.L., Tur-Kaspa R. Viral hepatitis in older adults. J. Am. Geriatr. Soc., 1997, vol. 45, no. 6, pp. 755–763.
  14. Meng X.J. Hepatitis E in the United States. An. NIH Research Workshop, 2012, no. 26, pp. 7–8.
  15. Rein D.B., Stevens G.A., Theaker J., Wittenborn J.S., Wiersma S.T. The global burden of hepatitis E virus genotypes 1 and 2 in 2005. Hepatology, 2012, vol. 55, no. 4, pp. 988–997.
  16. Van Steenbergen J.E., Tjon G., van den Hoek A., Koek A., Coutinho R.A., Bruisten S.M. Two years’ prospective collection of molecular and epidemiological data shows limited spread of hepatitis A virus outside risk groups in Amsterdam, 2000–2002. J. Infect. Dis., 2004, vol. 189, no. 3, pp. 471–82.
  17. Zhu F.C., Zhang J., Zhang X.F., Zhou C., Wang Z.Z., Huang S.J., Wang H., Yang C.L., Jiang H.M., Cai J.P., Wang Y.J., Ai X., Hu Y.M., Tang Q., Yao X., Yan Q., Xian Y.L., Wu T., Li Y.M., Miao J., Ng M.H., Shih J.W., Xia N.S. Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large-scale, randomised, double-blind placebo-controlled, phase 3 trial. Lancet, 2010, vol. 376, no. 9744, pp. 895–902.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2014 Malinnikova E.Y., Ilchenko L.Y., Mikhaylov M.I.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 64788 от 02.02.2016.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies