Parameters of mineral metabolism and bone density in young males with Helicobacter pylori-associated chronic gastritis

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Abstract

Here we present the current data on the chronic gastritis prevalence in young people. An issue regarding involvement of Helicobacter pylori infection in formation of low bone density is discussed. Examining the features of bone tissue metabolism in infection-associated chronic gastritis to optimize diagnostic algorithm was shown to be of high significance. In the study there were enrolled 200 employees working at the EMERCOM of Russia, who suffered from the acid-dependent gastric diseases and risk factors for reducing bone mineral density. Depending on the bone mineral density parameters, examining functional activity of the gastric mucosa, verification of the H. pylori infection, examining parameters of mineral metabolism, vitamin D level, parathyroid hormone, bone tissue remodeling markers was performed. It was shown that atrophic changes in the gastric mucosa the played a lead role in developing low bone mineral density.

About the authors

L. B. Drygina

The Nikiforov Russian Center of Emergency and Radiation Medicine of the Ministry of Russian Federation for Civil Defense, Emergencies and Elimination of Consequences of Natural Disasters

Author for correspondence.
Email: drygina@arcerm.spb.ru

Larisa B. Drygina, PhD, MD (Biology), Professor, Head of the Clinical Diagnostic Laboratory; Leading Researcher, Laboratory Diagnostics Department

194044, St. Petersburg, Academica Lebedeva str., 4/2.

Phone: +7 (812) 702-63-45, add. 2-304 (office).

Russian Federation

N. A. Dorofeytchik-Drygina

The Nikiforov Russian Center of Emergency and Radiation Medicine of the Ministry of Russian Federation for Civil Defense, Emergencies and Elimination of Consequences of Natural Disasters

Email: fake@neicon.ru

Orthodontist, Outpatient Department

St. Petersburg

Russian Federation

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Copyright (c) 2020 Drygina L.B., Dorofeytchik-Drygina N.A.

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