EPIDEMIC RISE IN THE INCIDENCE OF INFLUENZA IN ST. PETERSBURG IN 2016

Cover Page

Cite item

Abstract

Inf luenza and acute respiratory viral infections (ARVI) account for up to 90% of the total reported infectious morbidity annually in Russia. The economic damage from these infections reaches 86% of the economic losses associated with infectious diseases. As a result of antigenic drift or a shift, new variants of the inf luenza virus, including pandemic strains, appear. In 2009, an inf luenza pandemic arose due to the shifter version of the inf luenza A (H1N1) pdm09 virus. This virus caused epidemic rises of inf luenza in the world in subsequent years.

The aim of the study was to describe the epidemic process of inf luenza in January–March 2016 in St. Petersburg.

Materials and methods. The incidence of inf luenza and acute respiratory viral infections in St. Petersburg was recorded according to statistical coupons by age groups of the population. Examined nasopharyngeal f lushes received no later than 3–4 days from the onset of the disease, and in case of a lethal outcome — sectional material (bronchi, trachea, lungs, spleen tissues). The detection of RNA of inf luenza viruses was carried out in RT-PCR (Amplicenc Inf luenza virus A/B, Amplicenc Inf luenza virus A/H1-swine-FL, Amplicenc Inf luenza virus A типа-FL,  «Interlabservice», Moscow). Isolation of inf luenza viruses from the clinical material was carried out on culture by the MDSC cell. Isolates were typed in RTGA with diagnostic sera to reference and epidemic inf luenza viruses. Isolation of inf luenza viruses from the clinical material was carried out on culture by the MDSC cell. Isolates were typed in RTGA with diagnostic sera to reference and epidemic inf luenza viruses.

Results. In 2016, the incidence of inf luenza in St. Petersburg was 81.38 per 100 000 population and was 4.1 times higher than the incidence rate in 2015. The epidemic rise in the incidence of inf luenza and ARVI began with the 3rd calendar week, lasted 6 weeks, with a peak incidence at the 5th calendar week. In total, 398 675 people (7.6% of the population) were ill during this period, including adults — 184 658 (4%), children 0–14 years old — 214 017 or 31.5% of this age group. The greatest number of cases among children was registered in the group of 3–6 years — 87 766 (41.0%). Among the ill children, 86.2% attended pre-school children’s institutions (kindergartens). During the epidemic recovery in 2016, inf luenza viruses were detected in 297 people (46.2%): the inf luenza A (H1N1) virus pdm09 in 97.1% of cases, A (H3N2) — 0.6%, B — 2.3%. There were 102 deaths from complications after the inf luenza, including 101 cases of inf luenza A (H1N1) and A (H3N2) inf luenza A (H1N1) pdm09 confirmed by PCR. Among the dead 101 adults (including 2 pregnant women) and one child. All of them were not vaccinated against the f lu earlier. All deceased adults suffered from chronic physical illnesses.

About the authors

N. S. Bashketova

Head

Email: fake@neicon.ru

Department of the Federal service on Customers’ Rights Protection and Human Well-Being Surveillance for St. Petersburg

Russian Federation

I. G. Chkyhindzheriya

Head of Epidemiological Surveillance Department

Author for correspondence.
Email: epidnadzor@78.rospotrebnadzor.ru

Department of the Federal service on Customers’ Rights Protection and Human Well-Being Surveillance for St. Petersburg

Russian Federation

M. A. Bichurina

St. Petersburg Pasteur Institute

Email: fake@neicon.ru

PhD, MD (Medicine), Head of the Laboratory of Aetiology and Control of Viral Infections

Russian Federation

T. I. Krainova

Department of the Federal service on Customers’ Rights Protection and Human Well-Being Surveillance for St. Petersburg

Email: fake@neicon.ru

Specialist Of Epidemiological Surveillance Department

Russian Federation

E. A. Bryanceva

St. Petersburg Pasteur Institute

Email: fake@neicon.ru
PhD (Medicine), Senior Researcher; Laboratory of Aetiology and Control of Viral Infections Russian Federation

I. N. Lavrentieva

St. Petersburg Pasteur Institute

Email: fake@neicon.ru
PhD, MD (Medicine), Head of the Laboratory of Experimental Virology Russian Federation

L. P. Suhobaevskaya

St. Petersburg Pasteur Institute

Email: fake@neicon.ru

PhD (Medicine), Senior Researcher, Laboratory of Experimental Virology

Russian Federation

O. V. Degtjarev

Centre of Hygiene and Epidemiology in St. Petersburg

Email: fake@neicon.ru

Virologist

Russian Federation

T. E. Demakova

Centre of Hygiene and Epidemiology in St. Petersburg

Email: fake@neicon.ru

Bacteriologist

Russian Federation

References

  1. Бурцева Е.И., Федякина И.Т., Кириллова Е.С., Трушакова С.В., Феодоритова Е.Л., Беляев А.Л., Краснослободцев К.Г., Мукашева Е.А., Гарина Е.О., Оскерко Т.А., Аристова В.А., Львов Д.К. Заболеваемость гриппом в январе-марте 2016 г. в РФ, эпидемический и пандемический потенциал вируса гриппа А (H1N1)pdm09 // Пульмонология. 2016. Т. 26, № 4. С. 436–443. [Burtseva E.I., Fedyakina I.T., Kirillova E.S., Trushakova S.V., Feodoritova E.L., Belyaev A.L., Krasnoslobodtsev K.G., Mukasheva E.A., Garina E.O., Oskerko T.A., Aristova V.A., L’vov D.K. Flu morbidity in January-March, 2016, in Russian Federation. Epidemic and pandemic potential of A/H1N1pdm09 inf luenza virus. Pul’monologiya = Pulmonology, 2016, vol. 26, no. 4, pp. 436–443. doi: 10.18093/0869-0189-2016-26-4-436-443 (In Russ.)]
  2. Выделение вирусов гриппа в к леточных культурах и куриных эмбрионах и их идентификация: методические рекомендации № 0100/4430-06-34 (утверж дены Федеральной службой по надзору в сфере защиты прав потребителей и благополучия человека от 18 апреля 2006 г. № 100/4430-06-34). М., 2006. [Selection of inf luenza viruses in cell cultures and chicken embryos and their identification: methodical recommendations No. 0100/4430-06-34 (app. The Federal Service for Supervision of Consumer Rights Protection and Human Welfare on April 18, 2006). Мoscow: 2006.]
  3. Гендон Ю.З. Возможность предсказания пандемий гриппа // Журнал микробиологии, эпидемиологии и иммунобиологии. 2016. № 3. С.113–120. [Ghendon Yu.Z. Possibility of inf luenza pandemic prediction. Zhurnal mikrobiologii, epidemiologii i immunobiologii = Journal of Microbiology, Epidemiology and Immunobiology, 2016, no. 3, рр. 113–120. (In Russ.)]
  4. Гендон Ю.З. Свиной грипп H1N1/Калифорния — страсти и факты // Журнал микробиологии, эпидемиологии и иммунобиологии. 2010. № 4. С. 105–114. [Ghendon Yu.Z. Swine-origin inf luenza H1N1/California — passions and facts. Zhurnal mikrobiologii, epidemiologii i immunobiologii = Journal of Microbiology, Epidemiology and Immunobiology, 2010, no. 4, рр. 105–114. (In Russ.)]
  5. Карпова Л.С., Маринич И.Г., Поповцева Н.М., Столярова Т.П. Эпидемиология гриппа А (H1N1) Калифорния/07/09 среди населения 49 городов России в сезон 2009–2010 гг. // Журнал микробиологии, эпидемиологии и иммунобиологии. 2011. № 3. С. 14–20. [Karpova L.S., Marinich I.G., Popovtseva N.M., Stolyarova T.P. Epidemiology of inf luenza A/ California/07/09 (H1N1) in population of 49 cities in Russia in 2009–2010. Zhurnal mikrobiologii, epidemiologii i immunobiologii = Journal of Microbiology, Epidemiology and Immunobiology, 2011, no. 3, pp. 14–20. (In Russ.)]
  6. Карпова Л.С., Поповцева Н.М., Столярова Т.П., Столяров К.А., Коншина О.С., Соминина А.А. Эпидемиологические особенности эпидемии гриппа 2016 года в Санкт-Петербурге // Эпидемиология и вакцинопрофилактика. 2016. Т. 89, № 4. С. 13–21. [Karpova L.S., Popovtseva N.M., Carpenter T.P., Stolyarov K.A., Konshin O.S., Sominina A.A. Epidemiological characteristics of the epidemic inf luenza in 2016 in St. Petersburg. Epidemiologiya i vaktsinoprofilaktika = Epidemiology and Vaccinal Prevention, 2016, vol. 89, pp. 13–21. (In Russ.)]
  7. Карпова Л.С., Поповцева Н.М.. Столярова Т.П., Столяров К.А., Соминина А.А., Бурцева Е.И. Анализ эпидемии гриппа 2016 года и пандемии 2009 года по материалам двух национальных центров ВОЗ в Российской Федерации // Эпидемиология и вакцинопрофилактика. 2016. Т. 89, № 4. С. 4–12. [Karpova L.S., Popovtseva N.M., Stolyarova T.P., Stolyarov K.A., Sominina A.A., Burtseva E.I. Analysis of the f lu epidemic of 2016 and pandemie 2009 on materials of two national centres of the who in the Russian Federation. Epidemiologiya i vaktsinoprofilaktika = Epidemiology and Vaccinal Prevention, 2016, vol. 89, no. 4, pp. 4–12. (In Russ.)]
  8. Карпова Л.С., Соминина А.А., Бурцева Е.И., Пелих М.Ю., Федоритова Е.Л., Поповцева Н.М., Столярова Т.П., Киселев О.И. Сравнение эпидемий гриппа в России, вызванных пандемическим вирусом гриппа А (H1N1)pdm09 в период с 2009 по 2013 гг. // Вопросы вирусологии. 2015. Т. 60, № 3. С. 19–24. [Karpova L.S., Sominina A.A., Burtseva E.I., Pelikh M.Yu., Feodoritova E.L., Popovtseva N.M., Stolyarova T.P., Kiselev O.I. Comparison of the inf luenza epidemics in Russia caused by the pandemic virus A(H1N1)pdm09 within the period from 2009 to 2013. Voprosy virusologii = Problems of Virology, 2015, vol. 60, no. 3, pp. 19–24. (In Russ.)]
  9. Карпова Л.С., Соминина А.А., Пелих М.Ю., Поповцева Н.М., Столярова Т.П., Бурцева Е.И., Киселев О.И. Эпидемия гриппа в России в сезон 2012–2013 годов // Эпидемиология и вакцинопрофилактика. 2013. Т. 71, № 4. С. 7–13. [Karpova L.S., Sominina A.A., Pelikh M.Yu., Popovtseva N.M., Stolyarova T.P., Burtseva E.I., Kiselev O.I. Inf luenza epidemic in Russia in season 2012–2013. Epidemiologiya i vaktsinoprofilaktika = Epidemiology and Vaccinal Prevention, 2013, vol. 71, no 4, pp. 7–13. (In Russ.)]
  10. Львов Д.К., Бурцева Е.И., Колобухина Л.В., Федякина И.Т., Кириллова Е.С., Трушакова С.В., Феодоритова Е.Л., Беляев А.Л., Меркулова Л.Н., Краснослободцев К.Г., Мукашева Е.А., Гарина Е.О., Оскерко Т.А., Аристова В.А., Вартанян Р.В., Кистенева Л.Б., Дерябин П.Г., Прилипов А.Г., А льховский С.В., Кружкова И.С., Базарова М.В., Девяткин А.В. Вирусологические, эпидемиологические, к линические, молекулярно-генетические особенности эпидемии гриппа 2015–2016 гг.: доминирование вируса гриппа А(H1N1)pdm09 в России и странах Северного полушария // Вопросы вирусологии. 2016. Т. 61, № 4. С. 159–166. [L’vov D.K., Burtseva E.I., Kolobukhina L.V., Fedyakina I.T., Kirillova E.S., Trushakova S.V., Feodoritova E.L., Belyaev A.L., Merkulova L.N., Krasnoslobodtsev K.G., Mukasheva E.A., Garina E.O., Oskerko T.A., Aristova V.A., Vartanyan R.V., Kisteneva L.B., Deryabin P.G., Prilipov A.G., Al’khovskii S.V., Kruzhkova I.S., Bazarova M.V., Devyatkin A.V. Virological, epidemiological, clinical and molecular genetic features of inf luenza epidemics 2015–2016: dominance of inf luenza A(H1N1)pdm09 in Russia and the countries of the Northern hemisphere. Voprosy virusologii = Problems of Virology, 2016, vol. 61, no. 4, pp. 159–166. doi: 10.18821/0507-4088-2016-61-4-159-16 (In Russ.)]
  11. Притулина Ю.Г., Саломахин Г.Г., Пегусов С.М., Фролихина Е.Н. Сравнительная характеристика течения гриппа типа А/H1N1 в 2009 и 2016 годах // Здоровье и образование в 21 веке. 2016. Т. 18, № 2. С. 40–42. [Pritulina Y.G., Salomakhin G.G., Paegusov S.M., Frolikhina E.N. Comparative characteristics of the course Inf luenza А/H1N1 in 2009 and 2016 years. Zdorov’e i obrazovanie v 21 veke = Health and Education in 21st Century, 2016, vol. 18, no 2, pp. 40 –42. (In Russ.)]
  12. Яковлева Т.В., Брико Н.И., Герасимов А.Н., Салтыкова Т.С., Поздняков А.А. Сравнительная характеристика эпидемических сезонов гриппа 2015–2016 гг. и 2009–2010 гг. // Журнал микробиологии, эпидемиологии и иммунобиологии. 2017. № 1. С.11–19. [Yakovleva T.V., Briko N.I., Gerasimov A.N., Saltykova T.S., Pozdnyakov A.A. Comparative characteristic of epidemic inf luenza season 2015–2016 and 2009–2010. Zhurnal mikrobiologii, epidemiologii i immunobiologii = Journal of Microbiology, Epidemiology and Immunobiology, 2017, no. 1, рр. 11–19. (In Russ.)]
  13. Garten R.J., Davis C.T., Russell C.A., Shu B., Lindstrom S., Balish A., Sessio W.M. Antigenic avian abd genetic characteristics of swine-origin 2009 (H1N1) inf luenza virus circulating in humans. Science, 2009, vol. 325, no. 5937, рр. 197–201 doi: 10.1126/science.1176225
  14. WHO. New inf luenza А (H1N1) virus: global epidemiological situation. Weekly Epidemiol. Rec., 2009, vol. 84, no. 25, pp. 249–257.
  15. WHO. Pandemic (H1N1) 2009. Update 58.

Copyright (c) 2017 Bashketova N.S., Chkyhindzheriya I.G., Bichurina M.A., Krainova T.I., Bryanceva E.A., Lavrentieva I.N., Suhobaevskaya L.P., Degtjarev O.V., Demakova T.E.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies