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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Infection and Immunity</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Infection and Immunity</journal-title><trans-title-group xml:lang="ru"><trans-title>Инфекция и иммунитет</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2220-7619</issn><issn publication-format="electronic">2313-7398</issn><publisher><publisher-name xml:lang="en">SPb RAACI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">18075</article-id><article-id pub-id-type="doi">10.15789/2220-7619-PPO-18075</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">PATHOGENIC POTENTIAL OF BACTERIA OF THE GENUS AEROMONAS</article-title><trans-title-group xml:lang="ru"><trans-title>ПАТОГЕННЫЙ ПОТЕНЦИАЛ БАКТЕРИЙ РОДА AEROMONAS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-1804-5498</contrib-id><contrib-id contrib-id-type="spin">3441-1100</contrib-id><name-alternatives><name xml:lang="en"><surname>Logacheva</surname><given-names>Sophia Maximovna</given-names></name><name xml:lang="ru"><surname>Логачева</surname><given-names>Софья Максимовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Junior Researcher, Clinical Bacteriology Group of Tyumen Region Infection Pathology Research Institute, Tyumen, Russian Federation</p></bio><bio xml:lang="ru"><p>младший научный сотрудник группы клинической бактериологии ФБУН «Тюменский научно-исследовательский институт краевой инфекционной патологии» Роспотребнадзора</p></bio><email>info@tniikip.rospotrebnadzor.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9966-8454</contrib-id><contrib-id contrib-id-type="scopus">36958670900</contrib-id><contrib-id contrib-id-type="spin">7639-8300</contrib-id><name-alternatives><name xml:lang="en"><surname>Kataeva</surname><given-names>Lyubov</given-names></name><name xml:lang="ru"><surname>Катаева</surname><given-names>Любовь Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>DSc (Medicina), chief researcher, head of the bacteriological laboratory of Tyumen Region Infection Pathology Research Institute, Tyumen, Russian Federation</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, главный научный сотрудник, заведующая бактериологической лабораторией ФБУН «Тюменский научно-исследовательский институт краевой инфекционной патологии» Роспотребнадзора</p></bio><email>KataevaLV@Tniikip.rospotrebnadzor.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5420-0919</contrib-id><contrib-id contrib-id-type="scopus">23767533600</contrib-id><contrib-id contrib-id-type="spin">1967-8499</contrib-id><name-alternatives><name xml:lang="en"><surname>Stepanova</surname><given-names>Ksenia Borisovna</given-names></name><name xml:lang="ru"><surname>Степанова</surname><given-names>Ксения Борисовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Doctor of Medical Sciences, Director of Tyumen Region Infection Pathology Research Institute, Tyumen, RussianFederation</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, директор<italic> </italic>ФБУН «Тюменский научно-исследовательский институт краевой инфекционной патологии» Роспотребнадзора</p></bio><email>info@tniikip.rospotrebnadzor.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6289-6274</contrib-id><contrib-id contrib-id-type="scopus">7007079186</contrib-id><contrib-id contrib-id-type="spin">1212-5143</contrib-id><name-alternatives><name xml:lang="en"><surname>Stepanova</surname><given-names>Tatiana Fedorovna</given-names></name><name xml:lang="ru"><surname>Степанова</surname><given-names>Татьяна Федоровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>DSc (Medicina), Professor, chief researcher of the Tyumen Region Infection Pathology Research Institute, Tyumen, Russian Federation</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, профессор, главный научный сотрудник ФБУН «Тюменский научно-исследовательский институт краевой инфекционной патологии» Роспотребнадзора</p></bio><email>info@tniikip.rospotrebnadzor.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Tyumen Region Infectious Pathology Research Institute, Tyumen, Russia</institution></aff><aff><institution xml:lang="ru">ФБУН Тюменский научно-исследовательский институт краевой инфекционной патологии Роспотребнадзора, Тюмень, Россия</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2026-02-25" publication-format="electronic"><day>25</day><month>02</month><year>2026</year></pub-date><history><date date-type="received" iso-8601-date="2025-11-24"><day>24</day><month>11</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2026-02-19"><day>19</day><month>02</month><year>2026</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; , Logacheva S.M., Kataeva L., Stepanova K.B., Stepanova T.F.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; , Логачева С.М., Катаева Л.В., Степанова К.Б., Степанова Т.Ф.</copyright-statement><copyright-holder xml:lang="en">Logacheva S.M., Kataeva L., Stepanova K.B., Stepanova T.F.</copyright-holder><copyright-holder xml:lang="ru">Логачева С.М., Катаева Л.В., Степанова К.Б., Степанова Т.Ф.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://iimmun.ru/iimm/article/view/18075">https://iimmun.ru/iimm/article/view/18075</self-uri><abstract xml:lang="en"><p>Introduction. Bacteria of the genus <italic>Aeromonas</italic> are widespread in the environment, including marine and freshwater ecosystems, therapeutic mud, and wastewater. In recent years, human diseases caused by <italic>Aeromonas</italic> spp. have been increasingly reported, especially in individuals with weakened immune system. Being resistant to multiple drugs, these bacteria isolated from water bodies, fish, and seafood on fish farms pose a potential threat to aquaculture production and their spread throughout the environment. This review on study results assessing biological properties of <italic>Aeromonas</italic> bacteria, systematizing data on the phenotypic and molecular genetic mechanisms of their pathogenicity, defines a strategy for an interdisciplinary approach to diagnose and prevent <italic>Aeromonas</italic> infection. The objective of this review is to summarize and analyze data on the biochemical and molecular genetic characteristics of <italic>Aeromonas</italic> bacteria and determine their clinical and sanitary-epidemiological significance. Materials and Methods. Literature sources for this review were selected from the PubMed and Web of Science databases, and the eLIBRARY.ru scientific electronic library website. Initially, 98 scientific articles published between 2019 and 2025 were included in the work, covering the results from studies on the biological properties and prevalence of <italic>Aeromonas</italic> bacteria in patient biomaterials with bacterial infections, as well as their prevalence in environmental objects. The final version of the review included 65 references. Results. The scientific data presented here indicate a high frequency of detection of <italic>Aeromonas</italic> spp. in various environmental objects and those possessing pathogenicity factors. The presence of virulence and antimicrobial resistance determinants confirm their role in the development of human and animal as well as aquatic infections. Due to their ubiquitous distribution, metabolic and genetic characteristics, <italic>Aeromonas</italic> bacteria have been currently acquiring the status of a new pathogen and an indicator of resistance and virulence genes. Conclusions. The conducted analysis assessing results of studies on issues of identification, determination of phenotypic and genotypic characteristics, including antibiotic resistance underlying pathogenic potential of bacteria of the genus <italic>Aeromonas</italic>, suggests a need to further investigate these bacteria in the fields of healthcare, fish farming and agriculture.</p></abstract><trans-abstract xml:lang="ru"><p><italic>Введение.</italic> Бактерии рода <italic>Aeromonas</italic> широко распространены в окружающей среде: морских и пресноводных экосистемах, в лечебной грязи и сточных водах. В последние годы все чаще регистрируются заболевания человека, вызванные <italic>Aeromonas </italic><italic>spp</italic><italic>.</italic>, особенно у людей с ослабленным иммунитетом. Выделенные из водных объектов, рыб и морепродуктов на рыбных фермах и обладающих резистентностью к множеству лекарственных препаратов, они представляют потенциальную опасность для производства аквакультуры и распространения в объектах окружающей среды. Представленный обзор результатов проведенных исследований биологических свойств, бактерий рода <italic>Aeromonas,</italic> систематизирующий данные фенотипических и молекулярно-генетических механизмов их патогенности, определяет стратегию междисциплинарного подхода к проблеме диагностики и профилактики аэромонадной инфекции. <italic>Цель обзора</italic> – обобщить и проанализировать данные биохимических и молекулярно-генетических характеристик бактерий рода <italic>Aeromonas</italic>, определить их клиническое и санитарно-эпидемиологическое значение. <italic>Материалы и методы.</italic> Источники литературы для написания обзора подбирались в базах данных PubMed, Web of Science и на сайте <bold>научной электронной библиотеки — eLIBRARY.ru. Первоначально в работу было включено 98 научных статей, опубликованных в 2019-2025 гг. и касающихся результатов исследований биологических свойств и распространенности бактерий рода </bold><italic>Aeromonas</italic> в биоматериале пациентов при бактериальных инфекциях, а также распространенности их в объектах окружающей среды. В окончательный вариант обзора внесено 65 источников. <italic>Результаты.</italic> Представленные в обзоре научные данные указывают на высокую частоту обнаружения <italic>Aeromonas </italic>spp. в различных объектах окружающей среды и обладающих факторами патогенности. Наличие детерминант вирулентности и резистентности к антимикробным препаратам подтверждают их роль в развитии инфекций человека и животных, в том числе водных. Благодаря повсеместному распространению, метаболическим и генетическим особенностям бактерии рода <italic>Aeromonas</italic> в настоящее время приобретают статус нового патогена и индикатора генов резистентности и вирулентности. <italic>Выводы. </italic>Проведенный анализ результатов исследований, касающихся проблем идентификации, определения фенотипических и генотипических характеристик, в том числе антибиотикорезистентности, определяющих потенциал патогенности бактерий рода <italic>Aeromonas</italic>, свидетельствует о целесообразности дальнейшего изучения этих бактерий в сферах здравоохранения, рыбоводства и сельского хозяйства.</p></trans-abstract><kwd-group xml:lang="en"><kwd>review</kwd><kwd>bacteria of the genus Aeromonas</kwd><kwd>identification</kwd><kwd>biological properties</kwd><kwd>genes</kwd><kwd>resistance</kwd><kwd>virulence.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>обзор</kwd><kwd>бактерии рода Aeromonas</kwd><kwd>идентификация</kwd><kwd>биологические свойства</kwd><kwd>гены</kwd><kwd>резистентность</kwd><kwd>вирулентность.</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Басанкина В.М., Пруцаков С.В., Басанкин А.В. 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