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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="brief-report" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Infection and Immunity</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Infection and Immunity</journal-title><trans-title-group xml:lang="ru"><trans-title>Инфекция и иммунитет</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2220-7619</issn><issn publication-format="electronic">2313-7398</issn><publisher><publisher-name xml:lang="en">SPb RAACI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">17817</article-id><article-id pub-id-type="doi">10.15789/2220-7619-SAO-17817</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>SHORT COMMUNICATIONS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Short Communication</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Some aspects of prevalence and intrafamilial transmission of <italic>Helicobacter pylori</italic> among population of the Republic of Armenia</article-title><trans-title-group xml:lang="ru"><trans-title>Некоторые аспекты распространенности и внутрисемейной передачи <italic>Helicobacter pylori</italic> среди населения Республики Армения</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tsakanyan</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Цаканян</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="AM">Armenia</country></address><bio xml:lang="en"><p>PhD (Medicine), Senior Researcher of Microbiology Laboratory</p></bio><bio xml:lang="ru"><p>к.м.н., старший научный сотрудник микробиологической лаборатории </p></bio><email>nikolyan.sona@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Akinyan</surname><given-names>H. Sh.</given-names></name><name xml:lang="ru"><surname>Акинян</surname><given-names>А. Ш.</given-names></name></name-alternatives><address><country country="AM">Armenia</country></address><bio xml:lang="en"><p>MS, Subsidiary Researcher, Microbiologist</p></bio><bio xml:lang="ru"><p>магистр наук, младший научный сотрудник, микробиолог</p></bio><email>tsakanyananaida@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khachatryan</surname><given-names>T. S.</given-names></name><name xml:lang="ru"><surname>Хачатрян</surname><given-names>Т. С.</given-names></name></name-alternatives><address><country country="AM">Armenia</country></address><bio xml:lang="en"><p>PhD (Medicine), Senior Researcher of Reference Laboratory Center</p></bio><bio xml:lang="ru"><p>к.м.н., старший научный сотрудник референтного лабораторного центра </p></bio><email>tsakanyananaida@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Margaryan</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Маргарян</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="AM">Armenia</country></address><bio xml:lang="en"><p>PhD (Medicine), Senior Researcher of Reference Laboratory Center</p></bio><bio xml:lang="ru"><p>к.м.н., старший научный сотрудник референтного лабораторного центра</p></bio><email>tsakanyananaida@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Melik-Andreasyan</surname><given-names>G. G.</given-names></name><name xml:lang="ru"><surname>Мелик-Андреасян</surname><given-names>Г. Г.</given-names></name></name-alternatives><address><country country="AM">Armenia</country></address><bio xml:lang="en"><p>DSc (Medicine), Professor, Deputy Director of Reference Laboratory Center</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, зам. директора референтного лабораторного центра </p></bio><email>tsakanyananaida@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Center of Disease Control and Prevention, Ministry of Health Republic of Armenia</institution></aff><aff><institution xml:lang="ru">ГНКО «Национальный центр по контролю и профилактике заболеваний» Министерства здравоохранения Республики Армения</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-04-22" publication-format="electronic"><day>22</day><month>04</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-07-08" publication-format="electronic"><day>08</day><month>07</month><year>2025</year></pub-date><volume>15</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>361</fpage><lpage>365</lpage><history><date date-type="received" iso-8601-date="2024-11-17"><day>17</day><month>11</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2025-03-23"><day>23</day><month>03</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Tsakanyan A.V., Akinyan H.S., Khachatryan T.S., Margaryan A.V., Melik-Andreasyan .G.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Цаканян А.В., Акинян А.Ш., Хачатрян Т.С., Маргарян А.В., Мелик-Андреасян Г.Г.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Tsakanyan A.V., Akinyan H.S., Khachatryan T.S., Margaryan A.V., Melik-Andreasyan .G.</copyright-holder><copyright-holder xml:lang="ru">Цаканян А.В., Акинян А.Ш., Хачатрян Т.С., Маргарян А.В., Мелик-Андреасян Г.Г.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://iimmun.ru/iimm/article/view/17817">https://iimmun.ru/iimm/article/view/17817</self-uri><abstract xml:lang="en"><p><italic>Helicobacter pylori</italic> (HP) continues to be a serious public health issue worldwide, causing significant morbidity and mortality due to peptic ulcer disease and stomach cancer. This study was conducted to investigate the prevalence and intrafamilial transmission of HP infection among the population of Armenia. <italic>Materials and methods.</italic> In this study, the immunochromatographic method was used to detect HP microorganisms in stool samples. <italic>Results.</italic> The average age of the patients tested for HP was 29.9±2.0 years, with an age range from 2 months to 75 years. The study included 316 female patients, of whom 37.7% (95% CI: 32.4–43.0) tested positive for HP microorganisms, and 180 male patients, of whom 39.4% (95% CI: 32.3–46.5) tested positive. The highest prevalence of infection was observed in the following age groups: 50–59 years (65.1%), 40–49 years (47.1%), 30–39 years (41.1%), 20–29 years (40.4%), and 60–69 years (40.0%). <italic>Conclusion. </italic>Our research on patients with inflammatory diseases of the upper gastrointestinal tract, their family members, and others revealed a high infection rate of HP across all age groups. The study demonstrated a significant prevalence of HP infection among the population of Armenia, indicating a high likelihood of intrafamilial transmission.</p></abstract><trans-abstract xml:lang="ru"><p><italic>Helicobacter pylori</italic> (HP) продолжает оставаться серьезной проблемой общественного здравоохранения во всем мире, определяя существенную заболеваемость и смертность при язвенной болезни и раке желудка. Настоящее исследование было проведено с целью изучения распространенности и внутрисемейной передачи инфекции HP среди населения Армении. <italic>Материалы и методы.</italic> Для обнаружения микроорганизмов HP в образцах кала использовался иммунохроматографический метод. <italic>Результаты.</italic> Средний возраст пациентов, прошедших тестирование на HP, составил 29,9±2,0 года, возрастной диапазон — от 2 месяцев до 75 лет. В исследование были включены 316 пациентов женского пола и 180 пациентов мужского пола, из которых 37,7% (95% ДИ: 32,4–43,0) и 39,4% (95% ДИ: 32,3–46,5) соответственно имели положительный результат на обнаружение HP. Наибольшая распространенность инфекции наблюдалась в следующих возрастных группах: 50–59 лет (65,1%), 40–49 лет (47,1%), 30–39 лет (41,1%), 20–29 лет (40,4%) и 60–69 лет (40,0%). <italic>Заключение.</italic> Проведенное исследование пациентов с воспалительными заболеваниями верхних отделов желудочно-кишечного тракта, членов их семей и других лиц выявило высокую инфицированность HP во всех возрастных группах, а также значительную распространенность инфекции HP среди населения Армении, что указывает на высокую вероятность внутрисемейной передачи.</p></trans-abstract><kwd-group xml:lang="en"><kwd>prevalence</kwd><kwd>Helicobacter pylori infection</kwd><kwd>immunochromatographic method</kwd><kwd>intrafamilial transmission of H. pylori</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>распространенность</kwd><kwd>инфекция Helicobacter pylori</kwd><kwd>иммунохроматографический метод</kwd><kwd>внутрисемейная передача H. pylori</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Вартазарян Н.Д., Геворкян Дж.К., Члоян А.Е., Мирзабекян К.Г., Цаканян А.В. 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