Russian Journal of Infection and ImmunityRussian Journal of Infection and Immunity2220-76192313-7398SPb RAACI13710.15789/2220-7619-2013-3-251-262THE FEATURES OF HUMORAL IMMUNE RESPONSE FOR ANTIGENS OF OPPORTUNISTIC MICROORGANISMS IN CASE OF PHARYNX TONSILS HYPERTROPHY IN INFANTS AND PRESCHOOL CHILDRENShabaldinaE. V.PhD (Medicine), Associate Professor, Chief, Department of Otorhinolaryngology and Clinical Immunologyweit2007@yandex.ruShabaldinA. V.<p>PhD, MD (Medicine), Assistant Professor, Department of Otorhinolaryngology and Clinical Immunology, Kemerovo State Medical Academy; Leading Research Associate, Department of an Experimental and Clinical Cardiology, Research Institute for Complex Issues <br />of Cardiovascular Diseases, RAMS, Siberian Branch</p><p>650029, Russian Federation, Kemerovo, Voroshilova str., 22а</p>weit2007@yandex.ruLisachenkoG. V.PhD, MD (Medicine), Professor, Department of Pathophysiologyweit2007@yandex.ruDrozdovaM. V.PhD, MD (Medicine), Chief, Children’s Otorhinolaryngology Departmentweit2007@yandex.ruRiazantsevS. V.PhD, MD (Medicine), Professor, Deputy Directorweit2007@yandex.ruSimbirtsevA. S.PhD, MD (Medicine), Professor, Directorweit2007@yandex.ruFederal State Budgetary Educational Institution of the highest vocational training Kemerovo State Medical Academy
of Ministry of Health of RussiaFederal State Budgetary Institution «Research Institute for Complex Issues of Cardiovascular Diseases» under
the Siberian Branch of the Russian Academy of Medical SciencesSaint-Petersburg Research Institute of Ear, Throat, Nose and Speech the Ministry of Health of RussiaSaint-Petersburg State Federal Scientific Research Institute of especially pure biological products of Federal Medical Biological agency07072013332512620707201407072014Copyright © 2014, Shabaldina E.V., Shabaldin A.V., Lisachenko G.V., Drozdova M.V., Riazantsev S.V., Simbirtsev A.S.2014<div class="page" title="Page 11"><div class="layoutArea"><div class="column"><p><span><strong>Abstract</strong>. </span><span>Features of IgG and IgE immune response for opportunistic microbes of pharynx biotope in children with pharyngeal lymphoid hypertrophy and recurrent acute respiratory infections have been studied (base group). The ob tained data were compared with similar results for healthy children. It was shown that in children of base group in biotope of pharynx prevailed </span><span>S. pyogenes, S. pneumoniae, S. mutans, P. vulgaris </span><span>and </span><span>C. albicans. </span><span>It was demonstarted that in children of base group the IgG immune response was mainly induced by </span><span>S. pyogenes, S. pneumoniae, B. catharrhalis </span><span>and </span><span>H. influenzae</span><span>; and the IgE immune response — by </span><span>S. pyogenes, S. pneumoniae, S. aureus </span><span>and </span><span>H. influenzae</span><span>. The role of polyclonal induction of immune response to </span><span>S. pneumoniae </span><span>in pathogenesis of pharyngeal lymphoid hypertrophy and recurrent acute respiratory infections in children of early and preschool age has been detected. </span></p></div></div></div>opportunistic microbesS. pneumoniaeH. influenzaeatopic immune response.условно-патогенная микробиотаS. pneumoniaeH. influenzaeатопический иммунный ответ.[1. 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