Russian Journal of Infection and ImmunityRussian Journal of Infection and ImmunityИнфекция и иммунитет2220-76192313-7398SPb RAACI12910.15789/2220-7619-2013-3-213-216REVIEWSОБЗОРЫMODERN LABORATORY APPROACHES IN THE DIAGNOSIS OF CMV INFECTION IN IMMUNOCOMPROMISED PATIENTSСОВРЕМЕННЫЕ ПОДХОДЫ К ЛАБОРАТОРНОЙ ДИАГНОСТИКЕ ЦИТОМЕГАЛОВИРУСНОЙ ИНФЕКЦИИ У ИММУНОКОМПРОМЕТИРОВАННЫХ ПАЦИЕНТОВPadalkoE. Iu.ПадалкоЕ. Ю.
Belgium

PhD, Chief, Laboratory of Clinical Virology, Ghent University Hospital; Professor of Virology, Hasselt University

руководитель лаборатории клинической биологии и руководитель лаборатории клинической вирусологии и молекулярной диагностики, Госпиталь Университета г. Гента, профессор вирусологии факультета медицины и биомедицинской науки, Университет Хасалта 

okubar@list.ruGhent University Hospital, GhentГоспиталь Университета г. Гента, Гент07072013332132160707201407072014Copyright ©; 2014, Padalko E.I.Copyright ©; 2014, Падалко Е.Ю.2014Padalko E.I.Падалко Е.Ю.https://creativecommons.org/licenses/by/4.0https://iimmun.ru/iimm/article/view/129

Abstract. High susceptibility of immunocomromised human to infection (especially transplant recipients) is influenced by poor ability to combat it due to impaired cellmediated immunity plus high vulnerability to perturbations in the environment. Special considerations regarding infection in transplant recipients and particular approaches in laboratory diagnostics are based on profound analysis of the nature of viral infection in this population. In this article the modern knowledge about viral infections and laboratory diagnostic methods, particularly regarding CMV infection, in immunocompromised patients are discussed. 

Резюме. Высокая восприимчивость к инфекциям иммунокомпрометированных пациентов (в частности реципиентов при пересадке органов), обусловлена уязвимостью иммунной системы таких лиц к факторам внешней и внутренней среды, что требует формирования специальных подходов в лабораторной диагностике, основанной на глубоком и всестороннем понимании специфики вирусных инфекций у такой популяции пациентов. В рамках данной работы рассмотрены современные представления о течении инфекций, и, в частности, инфекции цитомегаловирусной природы у пациентов с пониженным иммунитетом, и даны объективные ориентиры для лабораторной диагностики этой инфекции. 

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