PATHOGENIC POTENTIAL OF BACTERIA OF THE GENUS AEROMONAS



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Abstract

Introduction. Bacteria of the genus Aeromonas are widespread in the environment, including marine and freshwater ecosystems, therapeutic mud, and wastewater. In recent years, human diseases caused by Aeromonas spp. have been increasingly reported, especially in individuals with weakened immune system. Being resistant to multiple drugs, these bacteria isolated from water bodies, fish, and seafood on fish farms pose a potential threat to aquaculture production and their spread throughout the environment. This review on study results assessing biological properties of Aeromonas bacteria, systematizing data on the phenotypic and molecular genetic mechanisms of their pathogenicity, defines a strategy for an interdisciplinary approach to diagnose and prevent Aeromonas infection. The objective of this review is to summarize and analyze data on the biochemical and molecular genetic characteristics of Aeromonas bacteria and determine their clinical and sanitary-epidemiological significance. Materials and Methods. Literature sources for this review were selected from the PubMed and Web of Science databases, and the eLIBRARY.ru scientific electronic library website. Initially, 98 scientific articles published between 2019 and 2025 were included in the work, covering the results from studies on the biological properties and prevalence of Aeromonas bacteria in patient biomaterials with bacterial infections, as well as their prevalence in environmental objects. The final version of the review included 65 references. Results. The scientific data presented here indicate a high frequency of detection of Aeromonas spp. in various environmental objects and those possessing pathogenicity factors. The presence of virulence and antimicrobial resistance determinants confirm their role in the development of human and animal as well as aquatic infections. Due to their ubiquitous distribution, metabolic and genetic characteristics, Aeromonas bacteria have been currently acquiring the status of a new pathogen and an indicator of resistance and virulence genes. Conclusions. The conducted analysis assessing results of studies on issues of identification, determination of phenotypic and genotypic characteristics, including antibiotic resistance underlying pathogenic potential of bacteria of the genus Aeromonas, suggests a need to further investigate these bacteria in the fields of healthcare, fish farming and agriculture.

About the authors

Sophia Maximovna Logacheva

Tyumen Region Infectious Pathology Research Institute, Tyumen, Russia

Email: info@tniikip.rospotrebnadzor.ru
ORCID iD: 0009-0005-1804-5498
SPIN-code: 3441-1100

Junior Researcher, Clinical Bacteriology Group of Tyumen Region Infection Pathology Research Institute, Tyumen, Russian Federation

Russian Federation, Tyumen Region Infection Pathology Research Institute, Tyumen, Russian Federation

Lyubov Kataeva

Tyumen Region Infectious Pathology Research Institute, Tyumen, Russia

Email: KataevaLV@Tniikip.rospotrebnadzor.ru
ORCID iD: 0000-0001-9966-8454
SPIN-code: 7639-8300
Scopus Author ID: 36958670900

DSc (Medicina), chief researcher, head of the bacteriological laboratory of Tyumen Region Infection Pathology Research Institute, Tyumen, Russian Federation

Russian Federation, Tyumen Region Infection Pathology Research Institute, Tyumen, Russian Federation

Ksenia Borisovna Stepanova

Tyumen Region Infectious Pathology Research Institute, Tyumen, Russia

Email: info@tniikip.rospotrebnadzor.ru
ORCID iD: 0000-0002-5420-0919
SPIN-code: 1967-8499
Scopus Author ID: 23767533600

Doctor of Medical Sciences, Director of Tyumen Region Infection Pathology Research Institute, Tyumen, Russian
Federation

Russian Federation, Tyumen Region Infection Pathology Research Institute, Tyumen, Russian Federation 625026, Tyumen region, Tyumen, Respubliki st., 147

Tatiana Fedorovna Stepanova

Tyumen Region Infectious Pathology Research Institute, Tyumen, Russia

Author for correspondence.
Email: info@tniikip.rospotrebnadzor.ru
ORCID iD: 0000-0002-6289-6274
SPIN-code: 1212-5143
Scopus Author ID: 7007079186

DSc (Medicina), Professor, chief researcher of the Tyumen Region Infection Pathology Research Institute, Tyumen, Russian Federation

Russian Federation, 625026, Tyumen region, Tyumen, Respubliki st., 147 Tyumen Region Infection Pathology Research Institute, Tyumen, Russian Federation

References

  1. Басанкина В.М., Пруцаков С.В., Басанкин А.В. Аэромоноз рыб: эпизоотологические особенности, клинические признаки, патологоанатомические изменения // Журнал: ветеринария Кубани. 2019. № 2. С. 21-23. Basankina V.M., Prutsakov S.V., Basankin A.V. Aeromonosis of fish: epizootiological features, clinical signs, and pathological changes. Journal: Kuban Veterinary Medicine, 2019, no. 2, pp. 21-23. (in Russ.) doi: 10.33861/2071-8020-2019-2-22-24
  2. Васильева О.В., Ульшина Д.В., Волынкина А.С., Писаренко С.В., Сирица Ю.В., Гнусарева О.А., Яценко Н.А., Куличенко А.Н. Опыт применения метода метагеномного секвенирования по фрагментам гена 16S рРНК для детекции и идентификации возбудителей природно-очаговых инфекций // Журнал микробиологии, эпидемиологии и иммунобиологии. 2025. № 102(2). С. 201-212. Vasilieva O.V., Ul’shina D.V., Volynkina A.S., Pisarenko S.V., Siritsa Y.V., Gnusareva O.A., Yatsenko N.A., Kulichenko A.N. Experience of applying the metagenomic sequencing method on fragments of the 16S rRNA gene for the detection and identification of natural focal infection pathogens. Journal of microbiology, epidemiology and immunobiology, 2025, no. 102(2), pp. 201-212. (in Russ.) doi: 10.36233/0372-9311-629
  3. Витомскова Е.А. Бактериальные болезни рыб открытых водоёмов крайнего северо-востока России // Journal of Agriculture and Environment. 2024. № 9(49). Vitomskova E.A. Bacterial Diseases of Fish in Open Water Bodies in the Far North-East of Russia. Journal of Agriculture and Environment, 2024, 9(49). (in Russ.) URL:ttps://jae.cifra.science/archive/9-49-2024-september/10.60797/JAE.2024.49.10 (дата обращения: 18.11.2025).
  4. doi: 10.60797/JAE.2024.49.10
  5. Доколин Д.А. Скрининг генетических биомаркеров для обнаружения патогенных аэромонад в продуктах питания и окружающей среде // Международная научно-практическая конференция молодых учёных и специалистов отделения сельскохозяйственных наук Российской академии наук. 2024. № 1. С. 74-78. Dokolin D.A. Screening of genetic biomarkers for detecting pathogenic Aeromonas in food and the environment. International Scientific and Practical Conference of Young Scientists and Specialists of the Department of Agricultural Sciences of the Russian Academy of Sciences, 2024, no. 1, pp. 74-78. (in Russ.) EDN: https://elibrary.ru/wyocad
  6. Доколин Д.А., Егоров Д.О., Флерова Е.А., Зайцева Ю.В. Исследование резистентности микроорганизмов в системе аквакультуры Oncorhynchus mykiss // Ветеринария и кормление. 2023. № 5. С. 22-26. Dokolin D.A., Egorov D.O., Flerova E.A., Zaitseva Yu.V. Investigation of microbial resistance in the aquaculture system Oncorhynchus mykiss. Veterinary medicine and feeding, 2023, no. 5, pp. 22-26. (in Russ.) doi: 10.30917/ATT-VK-1814-9588-2023-5-6
  7. Доколин Д.А., Зайцева Ю.В. Бактерии рода Aeromonas как потенциальный источник инфекций у рыб и земноводных // Экология и общество. 2020. № 23. С. 255-256. Dokolin D.A., Zaitseva Yu.V. Bacteria of the genus Aeromonas as a potential source of infections in fish and amphibians. Ecology and Society, 2020, no. 23, pp. 255-256. (in Russ.) EDN: https://elibrary.ru/zdtgle
  8. Ломакин А.А., Феоктистова Н.А, Сульдина Е.В., Нафеев А.А. Разработка и апробация схемы выделения и бактериологической идентификации Aeromonas hydrophila. Вестник Ульяновской государственной сельскохозяйственной академии // Инфекционные болезни и иммунология животных (биологические науки). 2024. № 2(54). С. 148-156. Lomakin A.A., Feoktistova N.A., Suldina E.V., and Nafeev A.A. Development and validation of a scheme for isolation and bacteriological identification of Aeromonas hydrophila. bulletin of the ulyanovsk state agricultural academy. Infectious Diseases and Animal Immunology (Biological Sciences), 2024, no. 2(54), pp. 148-156. (in Russ.) doi: 10.18286/1816-4501-2024-1-117-124
  9. Ломакин А.А., Феоктистова Н.А., Мастиленко А.В., Минаева А.Н. Изучение профилей чувствительности бактерий рода Aeromonas (A. hydrophila, A. veronii, A. caviae, A. salmonicida), выделенных из объектов ветеринарно-санитарного надзора // Вестник Ульяновской государственной сельскохозяйственной академии. 2023. № 3(63). С. 120-126. Lomakin A.A., Feoktistova N.A., Mastilenko A.V., Minaeva A.N. Study of the sensitivity profiles of Aeromonas bacteria (A. hydrophila, A. veronii, A. caviae, A. salmonicida) isolated from veterinary and sanitary surveillance objects. Bulletin of the Ulyanovsk State Agricultural Academy, 2023, no. 3(63), pp. 120-126. (in Russ.) doi: 10.18286/1816-4501-2023-3-120-126
  10. Минаева А.Н., Ломакин А.А., Васильев Д.А., Шестаков А.Г. Общая характеристика бактерий вида Aeromonas veronii // Евразийский союз ученых. 2021. № 2(83). С. 7-9. Minaeva A.N., Lomakin A.A., Vasilyev D.A., and Shestakov A.G. General characteristics of the Aeromonas veronii species. Eurasian union of scientists, 2021, no. 2(83), pp. 7-9. (in Russ.) EDN: https://elibrary.ru/pgtcha
  11. Родионова А.В., Сульдина Е.В., Васильев Д.А. Изучение устойчивости к некоторым физическим и химическим факторам бактерий рода Aeromonas. Аграрная наука и образование на современном этапе развития: опыт, проблемы и пути их решения // Материалы XI Международной научно-практической конференции. 2021. № 2. С. 379-385. Rodionova A.V., Suldina E.V., Vasilyev D.A. Study of the resistance of bacteria of the genus Aeromonas to some physical and chemical factors. Agrarian science and education at the current stage of development: experience, problems and ways of their solution. Materials of the XI International Scientific and Practical Conference, 2021, no. 2, pp. 379-385. (in Russ.) EDN: https://elibrary.ru/nkfwdj
  12. Чезганова Е.А., Ефимова О.С., Сахарова В.М., Ефимова А.Р., Созинов С.А., Исмагилов З.Р., Брусина Е.Б. Дополнительный резервуар госпитальных микроорганизмов в медицинских организациях // Журнал микробиологии, эпидемиологии и иммунобиологии. 2021. № 98(3). С. 266-275. Chezganova E.A., Efimova O.S., Sakharova V.M., Efimova A.R., Sozinov S.A., Ismagilov Z.R., Bru-sina E.B. The additional reservoir of hospital environment microorganisms at healthcare facilities. Journal of microbiology, epidemiology and immunobiology. Zhurnal mikrobiologii, èpidemiologii i immunobiologii, 2021, no. 98(3), pp. 266–275. (in Russ.) doi: 10.36233/0372-9311-120
  13. Яковенко П.П., Тищенко А.С., Максим Е.А., Кощаев А. Г., Алферов Д.О., Калошкина И.М. Оценка антагонистической активности и антибиотикорезистентности эпизоотически значимых видов аэромонад // Ветеринария Кубани. 2023. № 5. С. 43-45. Yakovenko P.P., Tishchenko A.S., Maxim E.A., Koshchaev A.G., Alferov D.O., Kaloshkina I.M. Assessment of the antagonistic activity and antibiotic resistance of epizootically significant species of Aeromonas. Kuban Veterinary Bulletin, 2023, no. 5, pp. 43-45. (in Russ.) doi: 10.33861/2071-8020-2023-5-43-45
  14. Abbott S.L., Cheung W.K., Janda J.M. The genus Aeromonas: biochemical characteristics, atypical reactions, and phenotypic identification schemes. J. Clin. Microbiol., 2003, vol. 41(6), no. 23, pp. 48-57. doi: 10.1128/JCM.41.6.2348-2357.2003
  15. Adah D.A., Saidu L., Oniye S.J., Adah A.S., Daoudu O.B., Ola-Fadunsin S.D. Molecular characterization and antibiotics resistance of Aeromonas species isolated from farmed African catfish Clarias gariepinus Burchell, 1822. BMC Vet. Res., 2024, no. 6, pp. 16-20(1). doi: 10.1186/s12917-023-03860-5
  16. Adah D.A., Saidu L., Oniye S.J., Raji M.A., Adah A.S., Daodu O.B, Obisesan O.M. . Multivariate analyses of water quality indices and incidence of Aeromonas species in water from different holding facilities in Kwara State, Nigeria. BMC Vet. Res., 2025, vol. 28; no. 21(1): 381. doi: 10.1186/s12917-025-04830-9
  17. Akbari M., Hadi N., Moradi F. Aeromonas veronii biovar sobria intestinal infection in a child girl after eating freshwater fish and drinking from a natural river in Southern Fars Province, Iran. IDCases, 2025, vol. 5, no. 40: e02245. doi: 10.1016/j.idcr.2025.e02245
  18. Behera B.K., Parida S.N., Kumar V., Swain H.S., Parida P.K., Bisai K., Dhar S., Das B.K. Aeromonas veronii is a lethal pathogen isolated from gut of infected labeo rohita: molecular insight to understand the bacterial virulence and its induced host immunity. Pathogens, 2023, no. 12(4): 598. doi: 10.3390/pathogens12040598
  19. Bhowmick U.D., Bhattacharjee S. Bacteriological, clinical and virulence aspects of Aeromonas-associated diseases in humans. Pol. J. Microbiol., 2018, no. 67(2), pp. 137-149. doi.:10.21307/pjm-2018-020
  20. Bing-Yao S., Wen H., Hui-Xin Y., Dan-Yang T., Pan-Yang J., Kang W., Cai-Gen Y., Xue-Hong S. Increased susceptibility to Aeromonas hydrophila infection in grass carp with antibiotic-induced intestinal dysbiosis. Aquaculture, 2022, 552 p. doi.:10.1016/j.aquaculture.2022.737969
  21. Bojar B.E., Craig A.T., Leduc A., Blumenthal M., May B., Ahmed A.S., Cahak C., Beattie R., Skwor T. Similar antimicrobial resistance and virulence profiles among Aeromonas isolates from recreational beaches, post-chlorinated wastewater and clinical samples in Milwaukee, Wisconsin USA. Sci. Total Environ., 2025, no. 970: 179035. doi.:10.1016/j.scitotenv.2025.179035
  22. Canellas A.L.B., Mello M.P., Paranhos R., Laport M.S. Genomic signatures of resistance and adaptability in Aeromonas and Pseudomonas from a Brazilian Hope Spot. Braz. J. Microbiol., 2025, no. 56(3), pp. 1641-1651. doi: 10.1007/s42770-025-01706-w
  23. Chen Y.W., Su Y.C., Chen W.Y., Wu J.H., Chen J.W., Shu-Li Su S.L., Chen C.S., Tsai P.F., Ko W.C., Chen P.L. Comprehensive genomic analysis of antimicrobial resistance in Aeromonas dhakensis. Microb. Drug. Resist., 2025, no. 31(4), pp. 97-106. doi: 10.1089/mdr.2024.0212
  24. Duarte M.L.O., Rodrigues D.L.N., de Lima G.B.V., Ariute J.C., Gouveia G.V., Gouveia J.J.S., Vasco Azevedo V., Brenig B., Guédon E., Tavares G.C., Costa M.M., Pereira U.P., Aburjaile F.F. In silico characterization of resistance and virulence genes in Aeromonas jandaei strains isolated from Oreochromis niloticus in Brazil. Microorganisms, 2025, vol. 8, no. 13(5): 1094. doi: 10.3390/microorganisms13051094
  25. Dubey S., Ager-Wick E., Kumar J., Karunasagar I., Iddya Karunasagar I., Bo Peng B., Evensen O, Sørum H., Hetron M., Munang’andu. Aeromonas species isolated from aquatic organisms, insects, chicken, and humans in India show similar antimicrobial resistance profiles. Front. Microbiol., 2022, no. 13: 1008870. doi: 10.3389/fmicb.2022.1008870
  26. Engert C.J., Medina-Morillo M., Sotil G., Aguinaga J.Y. Isolation, characterisation and virulence of Aeromonas spp. from peruvian rainbow trout: first description of A. popoffii- associated mortality. J. Fish Dis., 2025, no. 29: e14158. doi: 10.1111/jfd.14158
  27. Fernández-Bravo A., Figueras M.J. An update on the genus Aeromonas: taxonomy, epidemiology, and pathogenicity. Microorganisms, 2020, no. 8(1): 129. doi: 10.3390/microorganisms8010129
  28. Fuentes-Valencia M.A., Osornio-Esquivel J.L., Martínez Palacios C.A., Contreras-Ávila J.L., Barriga-Tovar E., Ingle-de la Mora G., Arellano-Torres A., Baizabal-Aguirre V.M., Bravo-Patiño A., Cajero-Juárez M., Valdez Alarcón J.J.. Bacterial and parasite co-infection in Mexican golden trout (Oncorhynchus chrysogaster) by Aeromonas bestiarum, Aeromonas sobria, Plesiomonas shigelloides and Ichthyobodo necator. BMC Vet. Res., 2022, no. 18(1): 137. doi: 10.1186/s12917-022-03208-5
  29. Gonzalez-Avila L.U., Loyola-Cruz M.A., Hernández-Cortez C., Bello-López J.M., Castro-Escarpulli G. Colistin resistance in Aeromonas spp. Int. J. Mol. Sci., 2021, no. 22(11): 5974. doi: 10.3390/ijms22115974
  30. Guio Oros J.F., Cobos E.A., Reyes J.V., Leal J.A., Large bone defects in the tibia secondary to Aeromonas hydrophila infection in open fractures: Report of two cases. Trauma Case Rep., 2025, no. 56, p. 101143. doi: 10.1016/j.tcr.2025.101143
  31. Hu H., Weng X., Pang G., Xiaobing Li X., Xia J., Gao X., He J., Li J., Qian D. Identification, pathogenicity, and antimicrobial resistance analysis of bacterial pathogenesis Aeromonas hydrophila from hybrid sturgeon (Huso dauricus ♀ × A. schrenckii ♂) in Zhejiang, China. Microorganisms, 2025, no. 13(2): 278. doi: 10.3390/microorganisms13020278
  32. Hu L., Wang X., Li Q. Methodology and application of multiplex PCR-dipstick DNA chromatography for the detection of eight respiratory bacterial pathogens. Front Cell Infect Microbiol., 2025, vol. 27; no. 15, p. 1558612. doi: 10.3389/fcimb.2025.1558612
  33. Hutchinson L.E., Franke J.D., Mailey B.A. Necrotizing fasciitis secondary to lake water inoculation with Aeromonas sobria. Medicine (Baltimore), 2021, no. 100(10), e24981. doi: 10.1097/MD.0000000000024981
  34. Jones D.C., LaMartina E.L., Lewis J.R., Dahl A.J., Nadig N., Szabo A., Newton R.J., Skwor T.A. One health and global health view of antimicrobial susceptibility through the "Eye" of Aeromonas: systematic review and meta-analysis. Int. J. Antimicrob. Agents, 2023, no. 62(2), p, 106848. doi: 10.1016/j.ijantimicag.2023.106848
  35. Kietsiri P., Sornsakrin S., Nou S., Oransathid W., Peerapongpaisarn D., Oransathid W., Nobthai P., Wassanarungroj P., Gonwong S., Sakpaisal P., Khemnu N., Sok S., Vannara S., Sivhour C., Krang S., Sovann L., Sovannarith E., Lurchachaiwong W., Chaudhury S., Ruamsap N., Lertsethtakarn P. Understanding the etiology of diarrheal illness in Cambodia in a case-control study from 2020 to 2023. Gut. Pathog., 2025, no. 17(1): 32. doi: 10.1186/s13099-025-00709-0
  36. Kosikowska U., Stec J., Andrzejczuk S., Mendrycka M., Pietras-Ożga D., Stępień-Pyśniak D. Plasmid-mediated fluoroquinolone resistance genes in quinolone-susceptible Aeromonas spp. phenotypes isolated from recreational surface freshwater reservoir. Front Cell Infect Microbiol., 2022, no. 12: 885360. doi: 10.3389/fcimb.2022.885360
  37. Lamy B., Baron S., Barraud O. Aeromonas: the multifaceted middleman in the One Health world. Curr. Opin. Microbiol., 2022, no. 65, pp. 24-32. doi: 10.1016/j.mib.2021.09.012
  38. Li Y., Yu K., Du X., Aixia Yan, Wang M., Kang Y., Li S., Wang Y., Wang L., Liu S., Peng T., Li J., Wang D., Zhenzhou Huang Z. Characterization of Aeromonas Strains Isolated from Adult Patients with Diarrhea and Aquatic Environments - Beijing Municipality, China, 2016-2022. China CDC Wkly, 2025, no. 7(4), pp. 121-129. doi: 10.46234/ccdcw2025.019
  39. Liu Y., Chen P., Lin F. Clinical characteristics and antibiotic sensitivity & resistance analysis of cases of orthopedic infections caused by Aeromonas hydrophila. BMC Musculoskelet Disord, 2025, no. 26(1): 560. doi: 10.1186/s12891-025-08806-6
  40. Makridin, A.S. Comprehensive bacteriological research of medical leeches of the species Hirudo verbana carena with pathology of the gastrointestinal tract. Global issues conference 2024: veterinary medicine, biology, biotechnology, agriculture, pedagogical and philological sciences, 2024, pp. 321-328. EDN: https://www.elibrary.ru/dbiojq
  41. Mancilla M., Ojeda A., Yuivar Y., Maritza Grandón, Grothusen H., Oyarzún M., Bisquertt A., Ugalde J.A., Fuentes F., Ibarra P., Bustos P. Major antigenic differences in Aeromonas salmonicida isolates correlate with the emergence of a new strain causing furunculosis in Chilean salmon farms. Front Cell. Infect. Microbiol., 2025, no. 15: 1508135. doi: 10.3389/fcimb.2025.1508135
  42. McDonald N.L., Wareham D.W., Bean D.C. Aeromonas and mcr-3: a critical juncture for transferable polymyxin resistance in gram-negative bacteria. Pathogens, 2024, no. 13(11): 921. doi: 10.3390/pathogens13110921
  43. Mendoza-Barberá E., Merino S., Tomás J. Surface glucan structures in Aeromonas spp. Mar Drugs., 2021, no. 19(11): 649. doi: 10.3390/md19110649
  44. Michova H., Pliva J., Jirsova A., Kamanova J. Cytotoxicity induced by Aeromonas schubertii is orchestrated by a unique set of type III secretion system effectors. Vet. Res., 2025, no. 56(1): 113. doi: 10.1186/s13567-025-01548-2
  45. Mizaeva T., Alieva K., Zulkarneev E., et al. Antibacterial Activity of Rainbow Trout Plasma: In Vitro Assays and Proteomic Analysis. Animals (Basel), 2023, no. 13(22): 3565. doi: 10.3390/ani13223565
  46. Montalvo E., Veiga F., Rodríguez H., Traglia G., Vay C., Almuzara M. Identificación y sensibilidad antibiótica de aislamientos de Aeromonas spp. en un Hospital Universitario de la ciudad de Buenos Aires. Rev. Argent. Microbiol., 2025, no. 57(2), pp. 105-113. doi: 10.1016/j.ram.2024.11.001
  47. Moradi F., Hadi N., Bazargani A., Abdi F., Ghorbanian N. Aeromonas characteristics in Iran, Southwest Asia; a systematic review and meta-analysis on epidemiology, reservoirs and antibiotic resistance profile from aquatic environments to human society during 2000-2023. BMC Vet. Res., 2025, no. 21(1): 107. doi: 10.1186/s12917-024-04431-y
  48. Neil B., Cheney G.L., Rosenzweig J.A., Sha J., Ashok K Chopra A.K. Antimicrobial resistance in aeromonads and new therapies targeting quorum sensing. Appl. Microbiol. Biotechnol., 2024, no. 108(1): 205. doi: 10.1007/s00253-024-13055-z
  49. Nokhwal A., Vaid R.K., Anand T., Verma R., Gulati R. Aeromonas species diversity, virulence characteristics, and antimicrobial susceptibility patterns in village freshwater aquaculture ponds in North India. Antibiotics (Basel), 2025, no. 14(3): 294. doi: 10.3390/antibiotics14030294
  50. Pintor-Cora A., Tapia O., Elexpuru-Zabaleta M., Ruiz de Alegría C., Rodríguez-Calleja J.M., Santos J.A., Ramos-Vivas J. Cytotoxicity and antimicrobial resistance of Aeromonas strains isolated from fresh produce and irrigation water. Antibiotics (Basel), 2023, vol. 3; no. 12(3): 511. doi: 10.3390/antibiotics12030511
  51. Pu W., Guo G., Yang N., Li Q., Yin F., Wang P., Zheng J., Zeng J. Three species of Aeromonas (A. dhakensis, A. hydrophila and A. jandaei) isolated from freshwater crocodiles (Crocodylus siamensis) with pneumonia and septicemia. Letters in Applied Microbiology, 2019, no. 68(3), pp. 212-218. doi: 10.1111/lam.13112
  52. Reyes-Rodríguez N.E., Talavera-González J.M., de-Anda F.R.G., Varela-Guerrero J.A., Zepeda-Velázquez A.P., Vega-Sánchez V. Aeromonas, an opportunistic pathogen present in wastewater in Tulancingo, Mexico. J. Water Health., 2025, no. 23(3), pp. 336-349. doi: 10.2166/wh.2025.242
  53. Seike S., Kobayashi H., Ueda M., Eizo Takahashi E., Okamoto K., Yamanaka H. Outer membrane vesicles released from Aeromonas Strains are involved in the biofilm formation. Front Microbiol., 2021, no. 11: 613650. doi: 10.3389/fmicb.2020.613650
  54. Skwor T., Stringer S., Haggerty J., Johnson J., Duhr S., Johnson M., Seckinger M., Stemme M. Prevalence of potentially pathogenic antibiotic-resistant Aeromonas spp. in treated urban wastewater effluents versus recipient riverine populations: a 3-year comparative study. Appl. Environ. Microbiol., 2020, no. 86(3): e02053-19. doi: 10.1128/AEM.02053-19
  55. Tabassum T., Islam A., Andalib K.M.S., Barnali Sarker B., Mia M., Ahmed K.S., Hossain H., Ahsan Habib A. Antibacterial activity of ocimum tenuiflorum against drug resistant bacteria isolated from raw beef. J. Microbiol. Biotechnol., 2025, no. 35: e2409028. doi: 10.4014/jmb.2409.09028
  56. Talagrand-Reboul E., Colston S.M., Graf J., Lamy B., Jumas-Bilak E. Comparative and evolutionary genomics of isolates provide insight into the pathoadaptation of Aeromonas. Genome Biol. Evol., 2020, no. 12(5), pp. 535-552. doi: 10.1093/gbe/evaa055
  57. Uechi K., Nishiyama N., Arakaki W., Nakano A., Uechi A., Nakamura T., Yamamoto K., Maeda S. An evaluation of the modified carbapenem inactivation method (mCIM) in conjunction with EDTA or sodium mercaptoacetate, for detecting metallo β-lactamase production for Aeromonas species harboring blaCphA. J. Infect. Chemother., 2025, no. 31(4): 102678. doi: 10.1016/j.jiac.2025.102678
  58. Van Bel N., van der Wielen P., Wullings B., van Rijn J., van der Mark E., Henk Ketelaars H., Hijnen W. Aeromonas species from non-chlorinated distribution systems and their competitive planktonic growth in drinking water. Appl. Environ Microbiol., 2021, no. 87(5): e02867-20. doi: 10.1128/AEM.02867-20
  59. Wang Y., Hou N., Rasooly R., Gu Y., He X. Prevalence and genetic analysis of chromosomal mcr-3/7 in Aeromonas from U.S. animal-derived samples. Front. Microbiol., 2021, no. 12: 667406. doi: 10.3389/fmicb.2021.667406
  60. Xin Wang, Jiwen Pan, Liqing Chen, Roushan Li. Prevalence, virulence-related genes and antimicrobial resistance of Aeromonas spp. from loach Misgurnus anguillicaudatus with skin ulcer and healthy controls in Southern China. Aquaculture, 2022, no. 552(6): 738040. doi: 10.1016/j.aquaculture.2022.738040
  61. Xiong C., Liu K., Wu Y., Ai Y, Yu Y., Mabrok M., Abu-Elala N., Li L., Hao Xu H., Li Y., Ye H., Mei H., Wu R. Decreased pathogenicity of triple-mutant of Aeromonas hydrophila flgK, flgL, flgE suggests its potential as a live attenuated vaccine for Carassius auratus. Fish Shellfish Immunol., 2025, no. 165: 110486. doi: 10.1016/j.fsi.2025.110486
  62. Xu T., Rasmussen-Ivey C.R., Moen F.S., Fernández-Bravo A., Lamy B., Beaz-Hidalgo R., Khan C.D., Escarpulli G.C., Yasin I.S.M., Figueras M.J., Azzam-Sayuti M., Karim M.M., Alam K.M.M., Le T.T.T., Phuong Thao N.H., Addo S., Duodu S., Ali S., Latif T., Mey S., Somony T., Liles M.R. A Global survey of hypervirulent Aeromonas hydrophila (vAh) identified vah strains in the lower mekong river basin and diverse opportunistic pathogens from farmed fish and other environmental sources. Microbiol Spectr. 2023; no. 11(2): e0370522. doi: 10.1128/spectrum.03705-22
  63. Yonezu M., Imamoto T. A fatal case of necrotizing soft tissue infection caused by Aeromonas hydrophila starting in the thigh. Cureus, 2025, vol. 3, no. 17(2): e78446. doi: 10.7759/cureus.78446
  64. Zdanowicz M., Mudryk Z.J., Perliński P. Abundance and antibiotic resistance of Aeromonas isolated from the water of three carp ponds. Vet. Res. Commun., 2020, no. 44(1), pp. 9-18. doi: 10.1007/s11259-020-09768-x
  65. Zhang J., Qiao D., Wang H., Zhao X., Jiang X., Zhu L., Zhang J., Li L., Kong X., Pei C. Mixed infection in common carp (Cyprinus carpio) caused by Aeromonas veronii, Aeromonas hydrophila, Plesiomonas shigelloides, and Citrobacter freundii. Animals (Basel), 2025, vol. 12; no. 15(6): 805.
  66. doi: 10.3390/ani15060805

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